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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARL4A All Species: 32.12
Human Site: S88 Identified Species: 41.57
UniProt: P40617 Number Species: 17
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P40617 NP_001032241.1 200 22615 S88 K L R P L W K S Y T R C T D G
Chimpanzee Pan troglodytes XP_001147147 220 24954 S88 K L R P L W K S Y T R C T D G
Rhesus Macaque Macaca mulatta XP_001099050 200 22556 S88 K L R P L W K S Y T R C T D G
Dog Lupus familis XP_548073 201 22148 S89 K L R P L W R S Y T R R T D G
Cat Felis silvestris
Mouse Mus musculus Q99PE9 201 22223 S89 K L R P L W R S Y T R R T D G
Rat Rattus norvegicus P61214 200 22570 S88 K L R P L W K S Y T R C T D G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519864 193 21567 R85 P L W K S Y S R C T D G I I Y
Chicken Gallus gallus P26990 175 20078 A91 L I F V V D C A D R D R I D E
Frog Xenopus laevis P51644 180 20567 V92 T Q G L I F V V D S N D R E R
Zebra Danio Brachydanio rerio NP_956612 201 22867 S89 K L R P L W R S Y T R C A D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40946 175 19987 V88 T Q G L I F V V D C A D R D R
Honey Bee Apis mellifera XP_001120491 207 22359 S91 K L R P L W K S Y T R C T D G
Nematode Worm Caenorhab. elegans Q10943 181 20503 V92 T Q G L I F V V D S N D R E R
Sea Urchin Strong. purpuratus XP_785283 193 21506 T95 I V Y V V D S T E K E R F D E
Poplar Tree Populus trichocarpa
Maize Zea mays P49076 181 20642 V92 T Q G L I F V V D S N D R D R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SHU5 205 23062 L107 L S E A R N E L H R I L T D N
Baker's Yeast Sacchar. cerevisiae P11076 181 20511 I89 Y R N T E G V I F V V D S N D
Red Bread Mold Neurospora crassa Q7RVM2 185 20961 N87 L W R H Y F Q N T Q G I I F V
Conservation
Percent
Protein Identity: 100 89 99 60.2 N.A. 60.7 99.5 N.A. 68 42 42.5 80 N.A. 42 54.1 40 50.5
Protein Similarity: 100 90.9 99.5 80 N.A. 81 100 N.A. 85.5 58 62 89.5 N.A. 59 70.5 59.5 69.5
P-Site Identity: 100 100 100 86.6 N.A. 86.6 100 N.A. 13.3 6.6 0 86.6 N.A. 6.6 100 0 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 100 N.A. 20 26.6 26.6 93.3 N.A. 20 100 26.6 26.6
Percent
Protein Identity: N.A. 40.5 N.A. 43.4 39.5 42
Protein Similarity: N.A. 60.5 N.A. 59.5 58 60
P-Site Identity: N.A. 6.6 N.A. 13.3 0 6.6
P-Site Similarity: N.A. 26.6 N.A. 26.6 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 6 0 0 0 6 0 0 6 0 6 0 0 % A
% Cys: 0 0 0 0 0 0 6 0 6 6 0 34 0 0 0 % C
% Asp: 0 0 0 0 0 12 0 0 28 0 12 28 0 73 6 % D
% Glu: 0 0 6 0 6 0 6 0 6 0 6 0 0 12 12 % E
% Phe: 0 0 6 0 0 28 0 0 6 0 0 0 6 6 0 % F
% Gly: 0 0 23 0 0 6 0 0 0 0 6 6 0 0 45 % G
% His: 0 0 0 6 0 0 0 0 6 0 0 0 0 0 0 % H
% Ile: 6 6 0 0 23 0 0 6 0 0 6 6 17 6 0 % I
% Lys: 45 0 0 6 0 0 28 0 0 6 0 0 0 0 0 % K
% Leu: 17 50 0 23 45 0 0 6 0 0 0 6 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 6 0 0 6 0 6 0 0 17 0 0 6 6 % N
% Pro: 6 0 0 45 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 23 0 0 0 0 6 0 0 6 0 0 0 0 0 % Q
% Arg: 0 6 50 0 6 0 17 6 0 12 45 23 23 0 23 % R
% Ser: 0 6 0 0 6 0 12 45 0 17 0 0 6 0 0 % S
% Thr: 23 0 0 6 0 0 0 6 6 50 0 0 45 0 0 % T
% Val: 0 6 0 12 12 0 28 23 0 6 6 0 0 0 6 % V
% Trp: 0 6 6 0 0 45 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 0 6 0 6 6 0 0 45 0 0 0 0 0 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _