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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARL4A All Species: 18.18
Human Site: T113 Identified Species: 23.53
UniProt: P40617 Number Species: 17
    Phosphosite Substitution
    Charge Score: -0.24
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P40617 NP_001032241.1 200 22615 T113 E R M E E A K T E L H K I T R
Chimpanzee Pan troglodytes XP_001147147 220 24954 T113 E R M E E A K T E L H K I T R
Rhesus Macaque Macaca mulatta XP_001099050 200 22556 T113 K R M E E A K T E L H K I T R
Dog Lupus familis XP_548073 201 22148 V114 E R L E E A K V E L H R I S R
Cat Felis silvestris
Mouse Mus musculus Q99PE9 201 22223 V114 E R L E E A K V E L H R I S K
Rat Rattus norvegicus P61214 200 22570 T113 E R M E E A K T E L H K I T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519864 193 21567 H110 E E A K T E L H K V T K F A E
Chicken Gallus gallus P26990 175 20078 I116 D R E M R D A I I L I F A N K
Frog Xenopus laevis P51644 180 20567 R117 M L Q E D E L R D A V L L V F
Zebra Danio Brachydanio rerio NP_956612 201 22867 T114 E R M E E A K T E L H K I T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40946 175 19987 R113 I I N D R E M R D A I I L I F
Honey Bee Apis mellifera XP_001120491 207 22359 M116 E R L E E A K M E L T R T A R
Nematode Worm Caenorhab. elegans Q10943 181 20503 R117 M L A E D E L R D A V L L V F
Sea Urchin Strong. purpuratus XP_785283 193 21506 P120 R P E T K G V P I M L I A N K
Poplar Tree Populus trichocarpa
Maize Zea mays P49076 181 20642 R117 M L N E D E L R D A V L L V F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SHU5 205 23062 N132 A N K Q D S R N A L P V A E V
Baker's Yeast Sacchar. cerevisiae P11076 181 20511 D114 M Q R M L N E D E L R N A A W
Red Bread Mold Neurospora crassa Q7RVM2 185 20961 R112 E A R E E L Q R M L N E D E L
Conservation
Percent
Protein Identity: 100 89 99 60.2 N.A. 60.7 99.5 N.A. 68 42 42.5 80 N.A. 42 54.1 40 50.5
Protein Similarity: 100 90.9 99.5 80 N.A. 81 100 N.A. 85.5 58 62 89.5 N.A. 59 70.5 59.5 69.5
P-Site Identity: 100 100 93.3 73.3 N.A. 66.6 100 N.A. 13.3 13.3 6.6 100 N.A. 0 60 6.6 0
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 100 N.A. 33.3 26.6 26.6 100 N.A. 20 73.3 26.6 20
Percent
Protein Identity: N.A. 40.5 N.A. 43.4 39.5 42
Protein Similarity: N.A. 60.5 N.A. 59.5 58 60
P-Site Identity: N.A. 6.6 N.A. 6.6 13.3 26.6
P-Site Similarity: N.A. 26.6 N.A. 33.3 26.6 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 12 0 0 45 6 0 6 23 0 0 23 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 0 0 6 23 6 0 6 23 0 0 0 6 0 0 % D
% Glu: 50 6 12 67 50 28 6 0 50 0 0 6 0 12 6 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 6 6 0 23 % F
% Gly: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 6 0 0 39 0 0 0 0 % H
% Ile: 6 6 0 0 0 0 0 6 12 0 12 12 39 6 0 % I
% Lys: 6 0 6 6 6 0 45 0 6 0 0 34 0 0 17 % K
% Leu: 0 17 17 0 6 6 23 0 0 67 6 17 23 0 6 % L
% Met: 23 0 28 12 0 0 6 6 6 6 0 0 0 0 0 % M
% Asn: 0 6 12 0 0 6 0 6 0 0 6 6 0 12 0 % N
% Pro: 0 6 0 0 0 0 0 6 0 0 6 0 0 0 0 % P
% Gln: 0 6 6 6 0 0 6 0 0 0 0 0 0 0 0 % Q
% Arg: 6 50 12 0 12 0 6 28 0 0 6 17 0 0 39 % R
% Ser: 0 0 0 0 0 6 0 0 0 0 0 0 0 12 0 % S
% Thr: 0 0 0 6 6 0 0 28 0 0 12 0 6 28 0 % T
% Val: 0 0 0 0 0 0 6 12 0 6 17 6 0 17 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _