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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARL4A All Species: 41.21
Human Site: T48 Identified Species: 53.33
UniProt: P40617 Number Species: 17
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P40617 NP_001032241.1 200 22615 T48 Q F N E F V N T V P T K G F N
Chimpanzee Pan troglodytes XP_001147147 220 24954 T48 Q F N E F V N T V P T K G F N
Rhesus Macaque Macaca mulatta XP_001099050 200 22556 T48 Q F N E F V N T V P T K G F N
Dog Lupus familis XP_548073 201 22148 S49 K F K E F V Q S V P T K G F N
Cat Felis silvestris
Mouse Mus musculus Q99PE9 201 22223 S49 K F K E F V Q S V P T K G F N
Rat Rattus norvegicus P61214 200 22570 T48 Q F N E F V N T V P T K G F N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519864 193 21567 F48 N T V P T I G F N T E K I K L
Chicken Gallus gallus P26990 175 20078 T51 T V G F N V E T V T Y K N V K
Frog Xenopus laevis P51644 180 20567 T55 T I G F N V E T V E Y K N I C
Zebra Danio Brachydanio rerio NP_956612 201 22867 T48 R F N E F V N T V P T K G F N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40946 175 19987 T51 T V G F N V E T V T Y K N V K
Honey Bee Apis mellifera XP_001120491 207 22359 T51 K F D Q Y L N T V P T I G F N
Nematode Worm Caenorhab. elegans Q10943 181 20503 T55 T I G F N V E T V E Y K N I S
Sea Urchin Strong. purpuratus XP_785283 193 21506 K54 N T E K I K C K K G S A K G S
Poplar Tree Populus trichocarpa
Maize Zea mays P49076 181 20642 T55 T I G F N V E T V E Y K N I S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SHU5 205 23062 D67 G I N F T V W D I G G Q E K I
Baker's Yeast Sacchar. cerevisiae P11076 181 20511 T48 E V I T T I P T I G F N V E T
Red Bread Mold Neurospora crassa Q7RVM2 185 20961 T48 K L G E V V T T I P T I G F N
Conservation
Percent
Protein Identity: 100 89 99 60.2 N.A. 60.7 99.5 N.A. 68 42 42.5 80 N.A. 42 54.1 40 50.5
Protein Similarity: 100 90.9 99.5 80 N.A. 81 100 N.A. 85.5 58 62 89.5 N.A. 59 70.5 59.5 69.5
P-Site Identity: 100 100 100 73.3 N.A. 73.3 100 N.A. 6.6 26.6 26.6 93.3 N.A. 26.6 60 26.6 0
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 100 N.A. 13.3 26.6 26.6 100 N.A. 26.6 93.3 33.3 20
Percent
Protein Identity: N.A. 40.5 N.A. 43.4 39.5 42
Protein Similarity: N.A. 60.5 N.A. 59.5 58 60
P-Site Identity: N.A. 26.6 N.A. 13.3 6.6 53.3
P-Site Similarity: N.A. 33.3 N.A. 26.6 26.6 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % A
% Cys: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 6 % C
% Asp: 0 0 6 0 0 0 0 6 0 0 0 0 0 0 0 % D
% Glu: 6 0 6 45 0 0 28 0 0 17 6 0 6 6 0 % E
% Phe: 0 45 0 34 39 0 0 6 0 0 6 0 0 50 0 % F
% Gly: 6 0 34 0 0 0 6 0 0 17 6 0 50 6 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 23 6 0 6 12 0 0 17 0 0 12 6 17 6 % I
% Lys: 23 0 12 6 0 6 0 6 6 0 0 73 6 12 12 % K
% Leu: 0 6 0 0 0 6 0 0 0 0 0 0 0 0 6 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 34 0 28 0 34 0 6 0 0 6 28 0 50 % N
% Pro: 0 0 0 6 0 0 6 0 0 50 0 0 0 0 0 % P
% Gln: 23 0 0 6 0 0 12 0 0 0 0 6 0 0 0 % Q
% Arg: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 12 0 0 6 0 0 0 17 % S
% Thr: 28 12 0 6 17 0 6 73 0 17 50 0 0 0 6 % T
% Val: 0 17 6 0 6 78 0 0 73 0 0 0 6 12 0 % V
% Trp: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 6 0 0 0 0 0 28 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _