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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC26A3 All Species: 25.76
Human Site: S242 Identified Species: 51.52
UniProt: P40879 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P40879 NP_000102.1 764 84505 S242 P S H T D P V S I F K V L Y S
Chimpanzee Pan troglodytes XP_527858 762 84270 S240 P S H N D P L S I F K V L V S
Rhesus Macaque Macaca mulatta XP_001090155 766 84849 S236 P S H E D P C S I F K V L Y S
Dog Lupus familis XP_540380 776 86204 S237 P A H T D P F S I F K V L N S
Cat Felis silvestris
Mouse Mus musculus Q9WVC8 757 83571 S235 P A Y S D P F S I F K V L E S
Rat Rattus norvegicus Q924C9 757 83350 S235 P A H S D P F S I F K V L E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507963 744 81520 S241 K R H S G P L S V V Y S T V A
Chicken Gallus gallus XP_415945 754 83386 V240 I I Y T L E S V F S Q I T D T
Frog Xenopus laevis NP_001089008 778 85897 S247 K N Y N G V L S I I Y T I I D
Zebra Danio Brachydanio rerio NP_001129155 745 82661 A244 P G I N G P L A I I Y T L V E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94225 782 87457 Y262 P R R S G P G Y L Y Y R I W D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FY46 685 75077 P241 A R S S K I V P I V E S I I A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 86.9 79.1 N.A. 80.3 80.8 N.A. 38.2 63.6 44.5 54.3 N.A. N.A. N.A. 23.5 N.A.
Protein Similarity: 100 98.5 91.5 87.2 N.A. 89.7 89.7 N.A. 58.9 78.9 62.9 72.6 N.A. N.A. N.A. 43.9 N.A.
P-Site Identity: 100 80 86.6 80 N.A. 66.6 73.3 N.A. 20 6.6 13.3 26.6 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 86.6 86.6 86.6 N.A. 86.6 86.6 N.A. 46.6 33.3 40 40 N.A. N.A. N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 25 0 0 0 0 0 9 0 0 0 0 0 0 17 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 50 0 0 0 0 0 0 0 0 9 17 % D
% Glu: 0 0 0 9 0 9 0 0 0 0 9 0 0 17 9 % E
% Phe: 0 0 0 0 0 0 25 0 9 50 0 0 0 0 0 % F
% Gly: 0 9 0 0 34 0 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 9 9 0 0 9 0 0 75 17 0 9 25 17 0 % I
% Lys: 17 0 0 0 9 0 0 0 0 0 50 0 0 0 0 % K
% Leu: 0 0 0 0 9 0 34 0 9 0 0 0 59 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 25 0 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 67 0 0 0 0 75 0 9 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 25 9 0 0 0 0 0 0 0 0 9 0 0 0 % R
% Ser: 0 25 9 42 0 0 9 67 0 9 0 17 0 0 50 % S
% Thr: 0 0 0 25 0 0 0 0 0 0 0 17 17 0 9 % T
% Val: 0 0 0 0 0 9 17 9 9 17 0 50 0 25 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 25 0 0 0 0 9 0 9 34 0 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _