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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC26A3 All Species: 32.12
Human Site: S46 Identified Species: 64.24
UniProt: P40879 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P40879 NP_000102.1 764 84505 S46 L K V C C S C S P Q K A K R I
Chimpanzee Pan troglodytes XP_527858 762 84270 S46 L K V C C S C S P Q K A K R I
Rhesus Macaque Macaca mulatta XP_001090155 766 84849 S46 L R V C F S C S P Q K A K R I
Dog Lupus familis XP_540380 776 86204 S46 L K V C C S C S T Q K A K K I
Cat Felis silvestris
Mouse Mus musculus Q9WVC8 757 83571 S46 L K G C C S C S S Q K A K K I
Rat Rattus norvegicus Q924C9 757 83350 S46 L K G C C S C S S Q K A K K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507963 744 81520 T53 I K Q A L S C T P K K V K H I
Chicken Gallus gallus XP_415945 754 83386 S46 L K L Y F R C S P Q R I K K V
Frog Xenopus laevis NP_001089008 778 85897 T53 V K K N C S C T S K K A L F I
Zebra Danio Brachydanio rerio NP_001129155 745 82661 V45 L K D Y F S G V S F S K L C L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94225 782 87457 I47 S L L S F L P I I T W L P K Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FY46 685 75077 T45 I P L Q H P D T S N E A R P P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 86.9 79.1 N.A. 80.3 80.8 N.A. 38.2 63.6 44.5 54.3 N.A. N.A. N.A. 23.5 N.A.
Protein Similarity: 100 98.5 91.5 87.2 N.A. 89.7 89.7 N.A. 58.9 78.9 62.9 72.6 N.A. N.A. N.A. 43.9 N.A.
P-Site Identity: 100 100 86.6 86.6 N.A. 80 80 N.A. 46.6 46.6 46.6 20 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 86.6 N.A. 66.6 73.3 66.6 26.6 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 0 0 0 0 67 0 0 0 % A
% Cys: 0 0 0 50 50 0 75 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % E
% Phe: 0 0 0 0 34 0 0 0 0 9 0 0 0 9 0 % F
% Gly: 0 0 17 0 0 0 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 17 0 0 0 0 0 0 9 9 0 0 9 0 0 67 % I
% Lys: 0 75 9 0 0 0 0 0 0 17 67 9 67 42 0 % K
% Leu: 67 9 25 0 9 9 0 0 0 0 0 9 17 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % N
% Pro: 0 9 0 0 0 9 9 0 42 0 0 0 9 9 9 % P
% Gln: 0 0 9 9 0 0 0 0 0 59 0 0 0 0 0 % Q
% Arg: 0 9 0 0 0 9 0 0 0 0 9 0 9 25 0 % R
% Ser: 9 0 0 9 0 75 0 59 42 0 9 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 25 9 9 0 0 0 0 0 % T
% Val: 9 0 34 0 0 0 0 9 0 0 0 9 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _