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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFC5
All Species:
27.27
Human Site:
S245
Identified Species:
50
UniProt:
P40937
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40937
NP_001123584.1
340
38497
S245
C
T
G
H
P
L
K
S
D
I
A
N
I
L
D
Chimpanzee
Pan troglodytes
XP_001156572
340
38434
S245
C
T
G
H
P
L
K
S
D
I
A
N
I
L
D
Rhesus Macaque
Macaca mulatta
XP_001084022
340
38392
S245
C
T
G
H
P
L
K
S
D
I
A
N
I
L
D
Dog
Lupus familis
XP_534696
410
45436
S315
C
T
G
H
P
L
K
S
D
I
A
N
I
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0F6
339
38078
T244
C
T
G
H
P
L
K
T
D
I
A
N
I
L
D
Rat
Rattus norvegicus
Q641W4
349
38638
P255
K
V
C
D
E
P
H
P
L
L
V
K
E
M
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080677
335
37956
S240
C
T
G
H
P
L
R
S
D
I
A
N
I
L
D
Zebra Danio
Brachydanio rerio
NP_001003862
334
37652
S239
C
T
G
H
P
L
R
S
D
I
A
N
I
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609399
332
37389
Q236
C
V
G
Y
P
L
R
Q
D
I
E
Q
I
L
K
Honey Bee
Apis mellifera
XP_393747
328
37019
L234
Y
S
C
V
G
H
P
L
P
I
D
I
K
N
I
Nematode Worm
Caenorhab. elegans
P34429
368
41157
K263
C
I
G
Q
P
T
P
K
E
M
K
E
V
V
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002302226
363
40477
Q267
C
T
G
N
P
L
P
Q
D
V
Q
Q
I
T
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38629
340
38185
D243
C
G
A
P
R
P
S
D
L
K
A
V
L
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.8
80.4
N.A.
94.1
36.3
N.A.
N.A.
N.A.
85.2
81.4
N.A.
60
62
46.2
N.A.
Protein Similarity:
100
99.7
99.4
81.7
N.A.
97
57.5
N.A.
N.A.
N.A.
94.7
91.7
N.A.
75.8
81.1
65.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
N.A.
N.A.
93.3
93.3
N.A.
53.3
6.6
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
N.A.
N.A.
100
100
N.A.
66.6
13.3
46.6
N.A.
Percent
Protein Identity:
55.6
N.A.
N.A.
N.A.
50
N.A.
Protein Similarity:
72.7
N.A.
N.A.
N.A.
70.8
N.A.
P-Site Identity:
46.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
60
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
62
0
0
0
0
% A
% Cys:
85
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
8
70
0
8
0
0
0
54
% D
% Glu:
0
0
0
0
8
0
0
0
8
0
8
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
77
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
54
0
8
8
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
0
70
0
8
70
0
16
% I
% Lys:
8
0
0
0
0
0
39
8
0
8
8
8
8
8
16
% K
% Leu:
0
0
0
0
0
70
0
8
16
8
0
0
8
62
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
54
0
8
0
% N
% Pro:
0
0
0
8
77
16
24
8
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
16
0
0
8
16
0
0
0
% Q
% Arg:
0
0
0
0
8
0
24
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
8
47
0
0
0
0
0
0
8
% S
% Thr:
0
62
0
0
0
8
0
8
0
0
0
0
0
8
0
% T
% Val:
0
16
0
8
0
0
0
0
0
8
8
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _