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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFC5
All Species:
27.27
Human Site:
S296
Identified Species:
50
UniProt:
P40937
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40937
NP_001123584.1
340
38497
S296
H
R
V
D
F
P
S
S
V
R
I
H
L
L
T
Chimpanzee
Pan troglodytes
XP_001156572
340
38434
S296
H
R
V
D
F
P
S
S
V
R
I
H
L
L
T
Rhesus Macaque
Macaca mulatta
XP_001084022
340
38392
S296
H
R
V
D
F
P
S
S
V
R
I
H
L
L
T
Dog
Lupus familis
XP_534696
410
45436
S366
H
R
V
D
F
P
S
S
V
R
V
H
L
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0F6
339
38078
S295
H
R
V
D
F
P
S
S
V
R
I
H
L
L
T
Rat
Rattus norvegicus
Q641W4
349
38638
Y306
K
T
F
P
M
A
E
Y
L
K
L
E
F
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080677
335
37956
S291
H
R
V
N
F
P
A
S
V
R
M
H
L
L
V
Zebra Danio
Brachydanio rerio
NP_001003862
334
37652
S290
H
R
V
D
F
P
P
S
I
R
M
G
L
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609399
332
37389
M287
V
M
R
L
E
L
P
M
S
V
M
N
K
L
I
Honey Bee
Apis mellifera
XP_393747
328
37019
P285
F
I
N
K
I
E
F
P
D
S
I
L
I
D
L
Nematode Worm
Caenorhab. elegans
P34429
368
41157
E314
F
T
L
D
I
P
D
E
A
M
S
A
I
I
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002302226
363
40477
D318
F
K
I
K
M
Q
S
D
I
R
V
P
L
I
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38629
340
38185
E294
D
Y
E
L
Q
N
E
E
T
R
V
H
L
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.8
80.4
N.A.
94.1
36.3
N.A.
N.A.
N.A.
85.2
81.4
N.A.
60
62
46.2
N.A.
Protein Similarity:
100
99.7
99.4
81.7
N.A.
97
57.5
N.A.
N.A.
N.A.
94.7
91.7
N.A.
75.8
81.1
65.4
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
0
N.A.
N.A.
N.A.
73.3
66.6
N.A.
6.6
6.6
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
N.A.
N.A.
93.3
80
N.A.
20
13.3
40
N.A.
Percent
Protein Identity:
55.6
N.A.
N.A.
N.A.
50
N.A.
Protein Similarity:
72.7
N.A.
N.A.
N.A.
70.8
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
0
8
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
54
0
0
8
8
8
0
0
0
0
8
0
% D
% Glu:
0
0
8
0
8
8
16
16
0
0
0
8
0
0
0
% E
% Phe:
24
0
8
0
54
0
8
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
54
0
0
0
0
0
0
0
0
0
0
54
0
0
0
% H
% Ile:
0
8
8
0
16
0
0
0
16
0
39
0
16
24
16
% I
% Lys:
8
8
0
16
0
0
0
0
0
8
0
0
8
0
8
% K
% Leu:
0
0
8
16
0
8
0
0
8
0
8
8
70
70
8
% L
% Met:
0
8
0
0
16
0
0
8
0
8
24
0
0
0
0
% M
% Asn:
0
0
8
8
0
8
0
0
0
0
0
8
0
0
8
% N
% Pro:
0
0
0
8
0
62
16
8
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
54
8
0
0
0
0
0
0
70
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
47
54
8
8
8
0
0
0
0
% S
% Thr:
0
16
0
0
0
0
0
0
8
0
0
0
0
0
54
% T
% Val:
8
0
54
0
0
0
0
0
47
8
24
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _