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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RFC5 All Species: 12.42
Human Site: T267 Identified Species: 22.78
UniProt: P40937 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P40937 NP_001123584.1 340 38497 T267 T T A Y R N I T E L K T L K G
Chimpanzee Pan troglodytes XP_001156572 340 38434 T267 T T A Y R N I T E L K T L K G
Rhesus Macaque Macaca mulatta XP_001084022 340 38392 T267 T T A Y R N I T E L K T L K G
Dog Lupus familis XP_534696 410 45436 M337 T T A Y R N I M E L K T L K G
Cat Felis silvestris
Mouse Mus musculus Q9D0F6 339 38078 M266 T T A Y K N I M E L K T L K G
Rat Rattus norvegicus Q641W4 349 38638 L277 I D E A Y K I L A H L W H L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001080677 335 37956 M262 T S A Y K N I M E L K T L K G
Zebra Danio Brachydanio rerio NP_001003862 334 37652 L261 T T A Y N Q I L E L K T L K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609399 332 37389 V258 L E D S F K T V E S A K Y A R
Honey Bee Apis mellifera XP_393747 328 37019 K256 S Y E L C Y C K I Q D I K L K
Nematode Worm Caenorhab. elegans P34429 368 41157 Q285 K K C M N T I Q T K L F E N G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002302226 363 40477 S289 A E S Y K R I S E I K T R K G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38629 340 38185 K265 T A H Y T L N K V R S A K G L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.8 80.4 N.A. 94.1 36.3 N.A. N.A. N.A. 85.2 81.4 N.A. 60 62 46.2 N.A.
Protein Similarity: 100 99.7 99.4 81.7 N.A. 97 57.5 N.A. N.A. N.A. 94.7 91.7 N.A. 75.8 81.1 65.4 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 86.6 13.3 N.A. N.A. N.A. 80 80 N.A. 6.6 0 13.3 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 13.3 N.A. N.A. N.A. 93.3 80 N.A. 6.6 6.6 13.3 N.A.
Percent
Protein Identity: 55.6 N.A. N.A. N.A. 50 N.A.
Protein Similarity: 72.7 N.A. N.A. N.A. 70.8 N.A.
P-Site Identity: 46.6 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 73.3 N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 54 8 0 0 0 0 8 0 8 8 0 8 0 % A
% Cys: 0 0 8 0 8 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 0 0 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 16 16 0 0 0 0 0 70 0 0 0 8 0 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 77 % G
% His: 0 0 8 0 0 0 0 0 0 8 0 0 8 0 0 % H
% Ile: 8 0 0 0 0 0 77 0 8 8 0 8 0 0 0 % I
% Lys: 8 8 0 0 24 16 0 16 0 8 62 8 16 62 8 % K
% Leu: 8 0 0 8 0 8 0 16 0 54 16 0 54 16 8 % L
% Met: 0 0 0 8 0 0 0 24 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 16 47 8 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 0 8 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 31 8 0 0 0 8 0 0 8 0 8 % R
% Ser: 8 8 8 8 0 0 0 8 0 8 8 0 0 0 0 % S
% Thr: 62 47 0 0 8 8 8 24 8 0 0 62 0 0 0 % T
% Val: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 8 0 70 8 8 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _