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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFC5
All Species:
33.03
Human Site:
Y310
Identified Species:
60.56
UniProt:
P40937
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40937
NP_001123584.1
340
38497
Y310
T
K
M
A
D
I
E
Y
R
L
S
V
G
T
N
Chimpanzee
Pan troglodytes
XP_001156572
340
38434
Y310
T
K
M
A
D
I
E
Y
R
L
S
V
G
T
N
Rhesus Macaque
Macaca mulatta
XP_001084022
340
38392
Y310
T
K
M
A
D
I
E
Y
R
L
S
V
G
T
N
Dog
Lupus familis
XP_534696
410
45436
Y380
T
K
M
A
D
I
E
Y
R
L
S
V
G
T
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0F6
339
38078
Y309
T
K
M
A
D
I
E
Y
R
L
S
V
G
T
S
Rat
Rattus norvegicus
Q641W4
349
38638
M320
K
E
I
G
Y
T
H
M
K
V
A
E
G
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080677
335
37956
Y305
V
K
M
A
D
I
E
Y
R
L
A
S
G
T
S
Zebra Danio
Brachydanio rerio
NP_001003862
334
37652
Y304
I
K
L
A
D
I
E
Y
R
L
A
S
G
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609399
332
37389
E301
I
V
K
L
A
Q
I
E
E
R
L
A
K
G
C
Honey Bee
Apis mellifera
XP_393747
328
37019
I299
L
I
I
K
L
A
E
I
E
K
R
V
S
I
G
Nematode Worm
Caenorhab. elegans
P34429
368
41157
E328
T
G
L
G
E
V
E
E
N
L
S
T
G
C
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002302226
363
40477
Y332
N
D
L
A
D
I
E
Y
R
L
S
F
G
C
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38629
340
38185
Y308
T
K
L
A
D
I
E
Y
S
I
S
K
G
G
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.8
80.4
N.A.
94.1
36.3
N.A.
N.A.
N.A.
85.2
81.4
N.A.
60
62
46.2
N.A.
Protein Similarity:
100
99.7
99.4
81.7
N.A.
97
57.5
N.A.
N.A.
N.A.
94.7
91.7
N.A.
75.8
81.1
65.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
13.3
N.A.
N.A.
N.A.
73.3
66.6
N.A.
0
13.3
33.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
N.A.
N.A.
86.6
86.6
N.A.
0
20
60
N.A.
Percent
Protein Identity:
55.6
N.A.
N.A.
N.A.
50
N.A.
Protein Similarity:
72.7
N.A.
N.A.
N.A.
70.8
N.A.
P-Site Identity:
66.6
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
70
8
8
0
0
0
0
24
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
8
% C
% Asp:
0
8
0
0
70
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
8
0
85
16
16
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
8
0
16
0
0
0
0
0
0
0
0
85
16
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
16
8
16
0
0
70
8
8
0
8
0
0
0
8
0
% I
% Lys:
8
62
8
8
0
0
0
0
8
8
0
8
8
0
0
% K
% Leu:
8
0
31
8
8
0
0
0
0
70
8
0
0
0
0
% L
% Met:
0
0
47
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
54
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
62
8
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
8
0
62
16
8
0
31
% S
% Thr:
54
0
0
0
0
8
0
0
0
0
0
8
0
54
0
% T
% Val:
8
8
0
0
0
8
0
0
0
8
0
47
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _