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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RFC3 All Species: 46.36
Human Site: T73 Identified Species: 72.86
UniProt: P40938 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P40938 NP_002906.1 356 40556 T73 K L R I E H Q T I T T P S K K
Chimpanzee Pan troglodytes XP_509625 356 40577 T73 K L R I E H Q T I T T P S K K
Rhesus Macaque Macaca mulatta XP_001102503 356 40568 T73 K L R I E H Q T I T T P S K K
Dog Lupus familis XP_534500 426 48443 T143 K L R I E H Q T I T T P S K K
Cat Felis silvestris
Mouse Mus musculus Q8R323 356 40508 T73 K L R I E H Q T I T T P S K K
Rat Rattus norvegicus NP_001009629 356 40461 T73 K L R I E H Q T I T T P S K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509935 356 40420 A73 K L R I E H Q A I T T P S K K
Chicken Gallus gallus NP_001006276 356 40321 S73 K L R I E H Q S I T A P S K K
Frog Xenopus laevis NP_001089570 356 40323 T73 K L R I E H Q T I T T P S K K
Zebra Danio Brachydanio rerio NP_958865 356 40309 S73 K L R I E H Q S I T T P S K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609494 356 40797 T73 R L R S E T M T F T T P S N R
Honey Bee Apis mellifera XP_624376 355 40561 T73 R L R M E T M T F E T P S K K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_779912 356 40599 T73 K L R I E H Q T F T T P S K A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38251 354 39923 Q74 R L K I D V R Q F V T A S N R
Red Bread Mold Neurospora crassa Q8X082 352 39902 V73 K I K I D A R V F Q T S S N R
Conservation
Percent
Protein Identity: 100 99.1 99.7 83.3 N.A. 97.1 96.9 N.A. 93.8 89.3 89.6 85.3 N.A. 59.5 68.5 N.A. 76.1
Protein Similarity: 100 99.7 99.7 83.5 N.A. 98 98.3 N.A. 96.9 96.6 95.5 94 N.A. 79.7 84.5 N.A. 89
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 86.6 100 93.3 N.A. 53.3 60 N.A. 86.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 100 100 N.A. 66.6 73.3 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 42.9 53
Protein Similarity: N.A. N.A. N.A. N.A. 62.6 71
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 26.6
P-Site Similarity: N.A. N.A. N.A. N.A. 60 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 0 7 0 0 7 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 87 0 0 0 0 7 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 34 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 74 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 87 0 0 0 0 67 0 0 0 0 0 0 % I
% Lys: 80 0 14 0 0 0 0 0 0 0 0 0 0 80 74 % K
% Leu: 0 94 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 7 0 0 14 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 87 0 0 0 % P
% Gln: 0 0 0 0 0 0 74 7 0 7 0 0 0 0 0 % Q
% Arg: 20 0 87 0 0 0 14 0 0 0 0 0 0 0 20 % R
% Ser: 0 0 0 7 0 0 0 14 0 0 0 7 100 0 0 % S
% Thr: 0 0 0 0 0 14 0 67 0 80 94 0 0 0 0 % T
% Val: 0 0 0 0 0 7 0 7 0 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _