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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFC3
All Species:
39.7
Human Site:
Y254
Identified Species:
62.38
UniProt:
P40938
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40938
NP_002906.1
356
40556
Y254
P
E
T
D
W
E
V
Y
L
R
E
T
A
N
A
Chimpanzee
Pan troglodytes
XP_509625
356
40577
Y254
P
E
T
D
W
E
V
Y
L
R
E
T
A
N
A
Rhesus Macaque
Macaca mulatta
XP_001102503
356
40568
Y254
P
E
T
D
W
E
V
Y
L
R
E
T
A
N
A
Dog
Lupus familis
XP_534500
426
48443
Y324
P
E
T
D
W
E
V
Y
L
R
E
T
A
N
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R323
356
40508
Y254
P
E
T
D
W
E
V
Y
L
R
E
T
A
N
A
Rat
Rattus norvegicus
NP_001009629
356
40461
Y254
P
E
T
D
W
E
V
Y
L
R
E
T
A
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509935
356
40420
Y254
P
E
T
D
W
E
V
Y
L
R
E
T
A
N
A
Chicken
Gallus gallus
NP_001006276
356
40321
C254
P
E
M
D
W
E
I
C
L
R
E
T
A
N
A
Frog
Xenopus laevis
NP_001089570
356
40323
Y254
P
E
T
D
W
E
V
Y
V
K
E
T
A
N
A
Zebra Danio
Brachydanio rerio
NP_958865
356
40309
Y254
P
E
T
D
W
E
V
Y
L
R
E
T
A
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609494
356
40797
F254
P
D
L
D
W
Q
V
F
L
R
E
T
A
S
Q
Honey Bee
Apis mellifera
XP_624376
355
40561
Y254
T
E
P
D
W
Q
V
Y
I
R
N
T
A
N
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779912
356
40599
F254
P
E
A
D
W
E
V
F
L
R
D
T
A
N
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38251
354
39923
V262
I
K
P
D
W
I
I
V
I
H
K
L
T
R
K
Red Bread Mold
Neurospora crassa
Q8X082
352
39902
L254
P
P
P
D
W
E
A
L
I
G
Q
I
A
K
E
Conservation
Percent
Protein Identity:
100
99.1
99.7
83.3
N.A.
97.1
96.9
N.A.
93.8
89.3
89.6
85.3
N.A.
59.5
68.5
N.A.
76.1
Protein Similarity:
100
99.7
99.7
83.5
N.A.
98
98.3
N.A.
96.9
96.6
95.5
94
N.A.
79.7
84.5
N.A.
89
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
80
86.6
100
N.A.
60
60
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
100
100
N.A.
86.6
73.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
42.9
53
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
62.6
71
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
7
0
0
0
0
0
94
0
67
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
100
0
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
0
80
0
0
0
80
0
0
0
0
74
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% H
% Ile:
7
0
0
0
0
7
14
0
20
0
0
7
0
0
0
% I
% Lys:
0
7
0
0
0
0
0
0
0
7
7
0
0
7
7
% K
% Leu:
0
0
7
0
0
0
0
7
74
0
0
7
0
0
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
7
0
0
80
0
% N
% Pro:
87
7
20
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
14
0
0
0
0
7
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
80
0
0
0
7
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% S
% Thr:
7
0
60
0
0
0
0
0
0
0
0
87
7
0
0
% T
% Val:
0
0
0
0
0
0
80
7
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _