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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SILV
All Species:
10
Human Site:
S446
Identified Species:
24.44
UniProt:
P40967
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40967
NP_008859.1
661
70255
S446
P
D
A
S
S
I
M
S
T
E
S
I
T
G
S
Chimpanzee
Pan troglodytes
XP_001169751
661
70174
S446
P
D
A
S
S
I
M
S
T
E
S
I
T
G
S
Rhesus Macaque
Macaca mulatta
XP_001113066
661
70301
S446
P
D
T
S
S
I
M
S
T
E
S
I
T
G
S
Dog
Lupus familis
XP_863198
581
64603
Y385
C
L
I
N
R
Y
G
Y
F
K
A
T
I
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q60696
626
65961
D427
S
I
S
P
L
L
D
D
T
D
T
I
M
L
V
Rat
Rattus norvegicus
Q6P7C7
572
63713
Y376
E
N
C
R
I
N
R
Y
G
Y
F
R
A
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514902
553
54201
A357
G
P
V
P
A
A
L
A
L
V
R
R
Q
A
P
Chicken
Gallus gallus
Q98917
763
77019
A452
V
A
A
A
T
P
G
A
T
A
A
D
V
A
V
Frog
Xenopus laevis
NP_001089087
597
65508
F401
T
T
A
A
A
G
C
F
I
Y
R
Y
G
Y
Y
Zebra Danio
Brachydanio rerio
NP_001029090
616
67361
C420
Q
A
P
N
I
N
G
C
V
I
Y
R
Y
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.1
27
N.A.
72.6
25.2
N.A.
35.7
41.1
31.4
32.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
96.3
44.9
N.A.
79.1
43.7
N.A.
48.1
55
50.2
51.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
13.3
0
N.A.
0
13.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
20
N.A.
40
6.6
N.A.
20
40
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
40
20
20
10
0
20
0
10
20
0
10
20
0
% A
% Cys:
10
0
10
0
0
0
10
10
0
0
0
0
0
0
0
% C
% Asp:
0
30
0
0
0
0
10
10
0
10
0
10
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
30
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
10
0
10
0
0
0
0
% F
% Gly:
10
0
0
0
0
10
30
0
10
0
0
0
10
40
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
20
30
0
0
10
10
0
40
10
0
20
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
0
10
0
0
10
10
10
0
10
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
30
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
0
20
0
20
0
0
0
0
0
0
0
0
0
% N
% Pro:
30
10
10
20
0
10
0
0
0
0
0
0
0
0
10
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
10
10
0
10
0
0
0
20
30
0
0
0
% R
% Ser:
10
0
10
30
30
0
0
30
0
0
30
0
0
0
40
% S
% Thr:
10
10
10
0
10
0
0
0
50
0
10
10
30
20
0
% T
% Val:
10
0
10
0
0
0
0
0
10
10
0
0
10
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
20
0
20
10
10
10
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _