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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OPRD1
All Species:
13.64
Human Site:
S255
Identified Species:
37.5
UniProt:
P41143
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41143
NP_000902.3
372
40413
S255
G
S
K
E
K
D
R
S
L
R
R
I
T
R
M
Chimpanzee
Pan troglodytes
Q5IS39
401
44883
N277
G
S
K
E
K
D
R
N
L
R
R
I
T
R
M
Rhesus Macaque
Macaca mulatta
Q9MYW9
400
44791
N276
G
S
K
E
K
D
R
N
L
R
R
I
T
R
M
Dog
Lupus familis
XP_544455
444
48253
S255
G
S
K
E
K
D
R
S
L
R
R
I
T
R
M
Cat
Felis silvestris
Mouse
Mus musculus
P32300
372
40543
S255
G
S
K
E
K
D
R
S
L
R
R
I
T
R
M
Rat
Rattus norvegicus
P33533
372
40431
S255
G
S
K
E
K
D
R
S
L
R
R
I
T
R
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510524
312
35765
V225
W
T
P
I
H
I
Y
V
I
I
K
A
L
I
N
Chicken
Gallus gallus
XP_427506
366
40984
N252
G
S
K
E
K
D
R
N
L
R
R
I
T
R
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571333
373
42502
N259
G
S
K
E
K
D
R
N
M
R
R
I
T
R
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.8
54.7
79.7
N.A.
93.8
93.8
N.A.
53.4
75
N.A.
65.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
67.3
66.2
80.8
N.A.
95.4
95.4
N.A.
64.7
84.4
N.A.
78.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
100
N.A.
100
100
N.A.
0
93.3
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
89
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
89
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
89
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
0
12
0
0
12
12
0
89
0
12
0
% I
% Lys:
0
0
89
0
89
0
0
0
0
0
12
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
78
0
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
89
% M
% Asn:
0
0
0
0
0
0
0
45
0
0
0
0
0
0
12
% N
% Pro:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
89
0
0
89
89
0
0
89
0
% R
% Ser:
0
89
0
0
0
0
0
45
0
0
0
0
0
0
0
% S
% Thr:
0
12
0
0
0
0
0
0
0
0
0
0
89
0
0
% T
% Val:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% V
% Trp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _