Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OPRK1 All Species: 31.82
Human Site: Y97 Identified Species: 77.78
UniProt: P41145 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41145 NP_000903.2 380 42645 Y97 M K T A T N I Y I F N L A L A
Chimpanzee Pan troglodytes Q5IS39 401 44883 Y109 M K T A T N I Y I F N L A L A
Rhesus Macaque Macaca mulatta Q9MYW9 400 44791 Y108 M K T A T N I Y I F N L A L A
Dog Lupus familis XP_544080 380 42713 Y97 M K T A T N I Y I F N L A L A
Cat Felis silvestris
Mouse Mus musculus P33534 380 42634 Y97 M K T A T N I Y I F N L A L A
Rat Rattus norvegicus P34975 380 42670 Y97 M K T A T N I Y I F N L A L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514649 423 48636 Y140 M K T A T N I Y I F N L A L A
Chicken Gallus gallus XP_426087 381 43124 Y98 M K T A T N I Y I F N L A M A
Frog Xenopus laevis NP_001089156 362 40659 F98 L V L V T L P F Q G T D I F M
Zebra Danio Brachydanio rerio NP_878306 377 42288 R98 N I Y I F N L R V A D A L V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.1 57 92.8 N.A. 93.6 94.2 N.A. 70.9 85.5 57.3 69.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 71 71.5 96.3 N.A. 97.6 97.6 N.A. 77.5 90.2 71.5 80.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 20 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 80 0 0 0 0 0 10 0 10 80 0 80 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 10 0 80 0 0 0 10 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 10 0 0 80 0 80 0 0 0 10 0 0 % I
% Lys: 0 80 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 10 0 0 10 10 0 0 0 0 80 10 70 0 % L
% Met: 80 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % M
% Asn: 10 0 0 0 0 90 0 0 0 0 80 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 80 0 90 0 0 0 0 0 10 0 0 0 10 % T
% Val: 0 10 0 10 0 0 0 0 10 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 80 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _