KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OPRL1
All Species:
4.55
Human Site:
Y14
Identified Species:
11.11
UniProt:
P41146
Number Species:
9
Phosphosite Substitution
Charge Score:
0.44
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41146
NP_000904.1
370
40693
Y14
A
P
F
W
E
V
I
Y
G
S
H
L
Q
G
N
Chimpanzee
Pan troglodytes
Q5IS39
401
44883
N34
P
S
P
G
S
W
V
N
L
S
H
L
D
G
N
Rhesus Macaque
Macaca mulatta
Q9MYW9
400
44791
N33
R
S
P
G
S
W
V
N
L
S
H
L
D
G
N
Dog
Lupus familis
XP_543110
370
40697
Y14
A
P
F
W
E
V
L
Y
G
S
H
L
Q
G
N
Cat
Felis silvestris
Mouse
Mus musculus
P35377
367
40472
E11
L
F
P
A
P
F
W
E
V
L
Y
G
S
H
F
Rat
Rattus norvegicus
P35370
367
40504
E11
L
F
P
A
P
Y
W
E
V
L
Y
G
S
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507098
368
41745
D12
F
H
P
S
L
W
E
D
F
Y
V
N
K
L
L
Chicken
Gallus gallus
XP_417424
368
41265
D12
F
P
A
H
I
L
E
D
P
D
L
R
K
L
L
Frog
Xenopus laevis
NP_001089156
362
40659
S8
M
D
L
S
L
A
E
S
F
E
A
A
Y
L
R
Zebra Danio
Brachydanio rerio
NP_991152
363
40852
I8
M
E
F
P
N
D
S
I
G
F
T
D
P
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.3
47.7
96.4
N.A.
94
93.5
N.A.
69.1
66.7
66.4
59.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
62.8
62.7
98.6
N.A.
96.2
96.2
N.A.
82.4
80.2
80.8
73.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
33.3
93.3
N.A.
0
0
N.A.
0
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
40
100
N.A.
6.6
6.6
N.A.
6.6
20
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
10
20
0
10
0
0
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
10
0
20
0
10
0
10
20
0
0
% D
% Glu:
0
10
0
0
20
0
30
20
0
10
0
0
0
0
0
% E
% Phe:
20
20
30
0
0
10
0
0
20
10
0
0
0
0
20
% F
% Gly:
0
0
0
20
0
0
0
0
30
0
0
20
0
40
0
% G
% His:
0
10
0
10
0
0
0
0
0
0
40
0
0
20
10
% H
% Ile:
0
0
0
0
10
0
10
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% K
% Leu:
20
0
10
0
20
10
10
0
20
20
10
40
0
30
20
% L
% Met:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
20
0
0
0
10
0
0
40
% N
% Pro:
10
30
50
10
20
0
0
0
10
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
10
0
10
10
% R
% Ser:
0
20
0
20
20
0
10
10
0
40
0
0
20
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
20
20
0
20
0
10
0
0
0
0
% V
% Trp:
0
0
0
20
0
30
20
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
20
0
10
20
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _