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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEP
All Species:
20.3
Human Site:
T37
Identified Species:
63.81
UniProt:
P41159
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41159
NP_000221.1
167
18641
T37
D
T
K
T
L
I
K
T
I
V
T
R
I
N
D
Chimpanzee
Pan troglodytes
O02750
146
16040
V18
K
T
L
I
K
T
I
V
T
R
I
N
D
I
S
Rhesus Macaque
Macaca mulatta
Q28504
167
18934
T37
D
T
K
T
L
I
K
T
I
V
T
R
I
N
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P41160
167
18690
T37
D
T
K
T
L
I
K
T
I
V
T
R
I
N
D
Rat
Rattus norvegicus
P50596
167
18847
T37
D
T
K
T
L
I
K
T
I
V
T
R
I
N
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509133
239
26761
T109
D
T
K
T
L
T
K
T
I
I
T
R
I
I
Q
Chicken
Gallus gallus
O42164
163
18165
I35
T
K
T
L
I
K
T
I
V
T
R
I
N
D
I
Frog
Xenopus laevis
NP_001089183
169
19395
T39
D
A
K
L
L
A
S
T
L
I
T
R
I
Q
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.8
89.8
N.A.
N.A.
83.2
82
N.A.
37.6
79
36
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
87.4
95.8
N.A.
N.A.
91
89.8
N.A.
49.7
86.8
53.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
N.A.
N.A.
100
100
N.A.
73.3
0
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
N.A.
N.A.
100
100
N.A.
80
20
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
0
13
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
0
0
0
0
0
0
0
0
0
0
0
13
13
50
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
13
13
50
13
13
63
25
13
13
75
25
13
% I
% Lys:
13
13
75
0
13
13
63
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
13
25
75
0
0
0
13
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
13
13
50
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
13
% Q
% Arg:
0
0
0
0
0
0
0
0
0
13
13
75
0
0
0
% R
% Ser:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
13
% S
% Thr:
13
75
13
63
0
25
13
75
13
13
75
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
13
13
50
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _