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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETV6
All Species:
16.06
Human Site:
S257
Identified Species:
35.33
UniProt:
P41212
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41212
NP_001978.1
452
53000
S257
E
S
H
P
K
P
S
S
P
R
Q
E
S
T
R
Chimpanzee
Pan troglodytes
XP_528737
452
53000
S257
E
P
H
P
K
P
S
S
P
R
Q
E
S
T
R
Rhesus Macaque
Macaca mulatta
XP_001083470
401
47245
P225
M
P
S
P
I
M
H
P
L
I
L
N
P
R
H
Dog
Lupus familis
XP_543812
745
83808
S550
E
P
H
P
K
P
S
S
P
R
Q
E
S
T
R
Cat
Felis silvestris
Mouse
Mus musculus
P97360
485
56387
V259
P
W
Q
E
S
T
R
V
I
Q
L
M
P
S
P
Rat
Rattus norvegicus
P41156
441
50404
Y258
S
F
E
S
I
E
S
Y
D
S
C
D
R
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521057
454
52210
S259
E
G
P
A
K
P
S
S
P
R
P
E
S
A
R
Chicken
Gallus gallus
P15062
485
55002
Y302
S
F
E
S
I
E
S
Y
D
S
C
D
R
L
T
Frog
Xenopus laevis
NP_001124423
448
52174
S254
E
P
I
N
K
P
N
S
P
R
Q
E
N
P
R
Zebra Danio
Brachydanio rerio
NP_571907
444
50811
A250
S
P
G
P
E
E
S
A
P
P
R
V
I
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01842
732
78555
N298
I
L
K
D
I
K
P
N
W
T
Q
Q
L
T
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
88.5
59.3
N.A.
83.3
26.3
N.A.
80.1
20.4
73.4
57
N.A.
20.8
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
88.5
60
N.A.
86.5
41.8
N.A.
84.5
36
82.7
71.2
N.A.
32.5
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
93.3
N.A.
0
6.6
N.A.
66.6
6.6
60
20
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
6.6
93.3
N.A.
13.3
13.3
N.A.
66.6
13.3
73.3
40
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
10
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
19
0
0
19
0
0
0
% D
% Glu:
46
0
19
10
10
28
0
0
0
0
0
46
0
0
0
% E
% Phe:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
28
0
0
0
10
0
0
0
0
0
0
0
10
% H
% Ile:
10
0
10
0
37
0
0
0
10
10
0
0
10
0
0
% I
% Lys:
0
0
10
0
46
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
10
0
19
0
10
19
10
% L
% Met:
10
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
10
0
0
0
10
10
0
10
% N
% Pro:
10
46
10
46
0
46
10
10
55
10
10
0
19
10
10
% P
% Gln:
0
0
10
0
0
0
0
0
0
10
46
10
0
10
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
46
10
0
19
10
46
% R
% Ser:
28
10
10
19
10
0
64
46
0
19
0
0
37
10
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
10
0
0
0
37
19
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _