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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LGTN
All Species:
17.88
Human Site:
S459
Identified Species:
32.78
UniProt:
P41214
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41214
NP_008824.2
584
64706
S459
V
M
K
L
P
W
D
S
L
L
T
R
C
L
E
Chimpanzee
Pan troglodytes
XP_514150
683
75708
S558
V
M
K
L
P
W
D
S
L
L
T
R
C
L
E
Rhesus Macaque
Macaca mulatta
XP_001086830
584
64481
S459
V
M
K
L
P
W
D
S
L
L
T
R
C
L
E
Dog
Lupus familis
XP_536109
584
64640
S459
V
M
K
L
P
W
D
S
L
L
T
R
C
F
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61211
570
62811
C446
V
T
K
L
P
W
D
C
L
L
T
R
C
L
K
Rat
Rattus norvegicus
Q5PPG7
570
62651
S446
V
M
K
L
P
W
D
S
L
L
T
R
C
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006322
315
34256
G213
E
V
E
G
K
K
P
G
N
S
V
S
T
D
T
Frog
Xenopus laevis
NP_001090591
583
64871
D459
I
F
T
L
K
W
D
D
L
L
S
R
C
L
E
Zebra Danio
Brachydanio rerio
NP_957456
590
66065
D465
V
E
M
L
K
W
D
D
L
I
S
R
T
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477481
563
61913
R436
L
I
E
L
Y
G
N
R
E
V
S
L
S
E
M
Honey Bee
Apis mellifera
XP_392122
528
58787
E421
M
K
T
K
A
N
V
E
T
V
M
M
E
D
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177291
597
65656
D478
P
S
E
I
H
K
K
D
V
G
S
T
F
V
G
Baker's Yeast
Sacchar. cerevisiae
Q04600
565
63973
N447
I
L
H
P
L
L
T
N
N
F
T
E
F
Y
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.4
97.5
87.5
N.A.
80.9
81.1
N.A.
N.A.
33
58.7
56.9
N.A.
35.6
35
N.A.
N.A.
Protein Similarity:
100
84.9
98.6
93.6
N.A.
88.8
89.3
N.A.
N.A.
43.3
74.3
74.4
N.A.
51.3
55.6
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
93.3
N.A.
N.A.
0
60
46.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
100
N.A.
N.A.
13.3
73.3
60
N.A.
46.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.3
26.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.4
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
54
0
0
% C
% Asp:
0
0
0
0
0
0
62
24
0
0
0
0
0
16
0
% D
% Glu:
8
8
24
0
0
0
0
8
8
0
0
8
8
8
39
% E
% Phe:
0
8
0
0
0
0
0
0
0
8
0
0
16
8
0
% F
% Gly:
0
0
0
8
0
8
0
8
0
8
0
0
0
0
16
% G
% His:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
8
0
8
0
0
0
0
0
8
0
0
0
0
8
% I
% Lys:
0
8
47
8
24
16
8
0
0
0
0
0
0
0
16
% K
% Leu:
8
8
0
70
8
8
0
0
62
54
0
8
0
54
0
% L
% Met:
8
39
8
0
0
0
0
0
0
0
8
8
0
0
8
% M
% Asn:
0
0
0
0
0
8
8
8
16
0
0
0
0
0
0
% N
% Pro:
8
0
0
8
47
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
62
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
39
0
8
31
8
8
0
0
% S
% Thr:
0
8
16
0
0
0
8
0
8
0
54
8
16
0
8
% T
% Val:
54
8
0
0
0
0
8
0
8
16
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
62
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _