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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LGTN
All Species:
25.15
Human Site:
S543
Identified Species:
46.11
UniProt:
P41214
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41214
NP_008824.2
584
64706
S543
P
A
P
G
A
K
D
S
L
Q
V
Q
I
Q
G
Chimpanzee
Pan troglodytes
XP_514150
683
75708
S642
P
A
P
G
A
K
D
S
L
Q
V
Q
I
Q
G
Rhesus Macaque
Macaca mulatta
XP_001086830
584
64481
S543
S
A
P
G
A
K
D
S
L
Q
V
Q
I
Q
G
Dog
Lupus familis
XP_536109
584
64640
S543
P
A
P
G
A
K
D
S
L
Q
V
Q
I
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61211
570
62811
S530
P
A
P
G
A
K
D
S
L
Q
V
Q
V
Q
G
Rat
Rattus norvegicus
Q5PPG7
570
62651
S530
P
A
P
G
A
K
D
S
L
Q
V
Q
V
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006322
315
34256
K293
H
A
L
K
C
K
V
K
K
S
D
L
P
L
L
Frog
Xenopus laevis
NP_001090591
583
64871
R543
A
I
P
G
S
K
E
R
V
Q
V
Q
I
Q
G
Zebra Danio
Brachydanio rerio
NP_957456
590
66065
R549
D
C
P
G
A
K
N
R
V
L
V
Q
I
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477481
563
61913
E521
K
L
P
H
Q
K
H
E
Q
L
Q
I
Q
G
N
Honey Bee
Apis mellifera
XP_392122
528
58787
T501
I
G
A
S
A
T
I
T
D
E
P
G
K
K
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177291
597
65656
Y562
E
L
P
G
K
K
G
Y
E
V
L
I
Q
G
G
Baker's Yeast
Sacchar. cerevisiae
Q04600
565
63973
A527
E
S
Q
T
F
K
C
A
E
V
Q
V
Q
G
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.4
97.5
87.5
N.A.
80.9
81.1
N.A.
N.A.
33
58.7
56.9
N.A.
35.6
35
N.A.
N.A.
Protein Similarity:
100
84.9
98.6
93.6
N.A.
88.8
89.3
N.A.
N.A.
43.3
74.3
74.4
N.A.
51.3
55.6
N.A.
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
13.3
60
60
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
N.A.
13.3
80
73.3
N.A.
13.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.3
26.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.4
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
54
8
0
62
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
8
0
0
8
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
47
0
8
0
8
0
0
0
0
% D
% Glu:
16
0
0
0
0
0
8
8
16
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
70
0
0
8
0
0
0
0
8
0
24
70
% G
% His:
8
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
8
0
0
0
0
16
47
0
0
% I
% Lys:
8
0
0
8
8
93
0
8
8
0
0
0
8
8
0
% K
% Leu:
0
16
8
0
0
0
0
0
47
16
8
8
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% N
% Pro:
39
0
77
0
0
0
0
0
0
0
8
0
8
0
8
% P
% Gln:
0
0
8
0
8
0
0
0
8
54
16
62
24
62
0
% Q
% Arg:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% R
% Ser:
8
8
0
8
8
0
0
47
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
8
0
8
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
8
0
16
16
62
8
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _