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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LGTN All Species: 19.39
Human Site: S88 Identified Species: 35.56
UniProt: P41214 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41214 NP_008824.2 584 64706 S88 P T V Y T L W S Y P D L L P T
Chimpanzee Pan troglodytes XP_514150 683 75708 S187 P T V Y T L W S Y P D L L P T
Rhesus Macaque Macaca mulatta XP_001086830 584 64481 S88 P T V Y T L W S Y P D L L P T
Dog Lupus familis XP_536109 584 64640 S88 P T V Y T L W S Y P D L L P T
Cat Felis silvestris
Mouse Mus musculus Q61211 570 62811 A88 P T V Y T L W A Y P D I L P T
Rat Rattus norvegicus Q5PPG7 570 62651 S88 P T V Y T L W S H P D L L P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006322 315 34256
Frog Xenopus laevis NP_001090591 583 64871 K88 P T V Y T L W K Y P D L L P A
Zebra Danio Brachydanio rerio NP_957456 590 66065 R88 P T V Y T L W R C P N M L P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477481 563 61913 P88 L Y T L W I V P D I L P Y F T
Honey Bee Apis mellifera XP_392122 528 58787 T88 A L L P T I Y T L W H H P N L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_177291 597 65656 E88 P T V F A L W E A P E M L P S
Baker's Yeast Sacchar. cerevisiae Q04600 565 63973 L88 S C W E Y P A L L P I V L T H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.4 97.5 87.5 N.A. 80.9 81.1 N.A. N.A. 33 58.7 56.9 N.A. 35.6 35 N.A. N.A.
Protein Similarity: 100 84.9 98.6 93.6 N.A. 88.8 89.3 N.A. N.A. 43.3 74.3 74.4 N.A. 51.3 55.6 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 86.6 N.A. N.A. 0 86.6 66.6 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 0 86.6 80 N.A. 13.3 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32.3 26.2 N.A.
Protein Similarity: N.A. N.A. N.A. 52.4 45.3 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 0 8 8 8 0 0 0 0 0 24 % A
% Cys: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 54 0 0 0 0 % D
% Glu: 0 0 0 8 0 0 0 8 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 8 8 0 0 8 % H
% Ile: 0 0 0 0 0 16 0 0 0 8 8 8 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % K
% Leu: 8 8 8 8 0 70 0 8 16 0 8 47 77 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % N
% Pro: 70 0 0 8 0 8 0 8 0 77 0 8 8 70 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 8 0 0 0 0 0 0 39 0 0 0 0 0 0 8 % S
% Thr: 0 70 8 0 70 0 0 8 0 0 0 0 0 8 47 % T
% Val: 0 0 70 0 0 0 8 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 8 0 8 0 70 0 0 8 0 0 0 0 0 % W
% Tyr: 0 8 0 62 8 0 8 0 47 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _