Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LGTN All Species: 9.09
Human Site: T210 Identified Species: 16.67
UniProt: P41214 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41214 NP_008824.2 584 64706 T210 G S V Q M D S T L Q G D M R H
Chimpanzee Pan troglodytes XP_514150 683 75708 T309 G S V Q M D S T L Q G D M R H
Rhesus Macaque Macaca mulatta XP_001086830 584 64481 T210 G S V Q V D S T L Q G D M R H
Dog Lupus familis XP_536109 584 64640 M210 S I T A D P A M Q E D L R C L
Cat Felis silvestris
Mouse Mus musculus Q61211 570 62811 K210 L G L Q G N L K S L T L D G E
Rat Rattus norvegicus Q5PPG7 570 62651 R210 L G L H G N L R S L S L E G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006322 315 34256
Frog Xenopus laevis NP_001090591 583 64871 V210 G K A A S Q E V S E A Q D P Q
Zebra Danio Brachydanio rerio NP_957456 590 66065 E210 G E E C E E E E E E V K D S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477481 563 61913 E209 P A L G S E T E R R K T A S P
Honey Bee Apis mellifera XP_392122 528 58787 L195 K P P L R P N L G P P N I D I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_177291 597 65656 I211 A P G S G E D I L D T S A S T
Baker's Yeast Sacchar. cerevisiae Q04600 565 63973 E202 N I S S K Q I E S S E Q I K A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.4 97.5 87.5 N.A. 80.9 81.1 N.A. N.A. 33 58.7 56.9 N.A. 35.6 35 N.A. N.A.
Protein Similarity: 100 84.9 98.6 93.6 N.A. 88.8 89.3 N.A. N.A. 43.3 74.3 74.4 N.A. 51.3 55.6 N.A. N.A.
P-Site Identity: 100 100 93.3 0 N.A. 6.6 0 N.A. N.A. 0 6.6 6.6 N.A. 0 0 N.A. N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 20 13.3 N.A. N.A. 0 13.3 20 N.A. 33.3 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32.3 26.2 N.A.
Protein Similarity: N.A. N.A. N.A. 52.4 45.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 16 0 0 8 0 0 0 8 0 16 0 8 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 8 24 8 0 0 8 8 24 24 8 0 % D
% Glu: 0 8 8 0 8 24 16 24 8 24 8 0 8 0 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 39 16 8 8 24 0 0 0 8 0 24 0 0 16 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 24 % H
% Ile: 0 16 0 0 0 0 8 8 0 0 0 0 16 0 8 % I
% Lys: 8 8 0 0 8 0 0 8 0 0 8 8 0 8 0 % K
% Leu: 16 0 24 8 0 0 16 8 31 16 0 24 0 0 8 % L
% Met: 0 0 0 0 16 0 0 8 0 0 0 0 24 0 0 % M
% Asn: 8 0 0 0 0 16 8 0 0 0 0 8 0 0 0 % N
% Pro: 8 16 8 0 0 16 0 0 0 8 8 0 0 8 8 % P
% Gln: 0 0 0 31 0 16 0 0 8 24 0 16 0 0 8 % Q
% Arg: 0 0 0 0 8 0 0 8 8 8 0 0 8 24 0 % R
% Ser: 8 24 8 16 16 0 24 0 31 8 8 8 0 24 8 % S
% Thr: 0 0 8 0 0 0 8 24 0 0 16 8 0 0 8 % T
% Val: 0 0 24 0 8 0 0 8 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _