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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LGTN
All Species:
13.94
Human Site:
T247
Identified Species:
25.56
UniProt:
P41214
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41214
NP_008824.2
584
64706
T247
E
A
P
E
D
T
S
T
R
G
L
N
Q
D
S
Chimpanzee
Pan troglodytes
XP_514150
683
75708
T346
E
A
P
E
D
T
S
T
R
G
L
N
Q
D
S
Rhesus Macaque
Macaca mulatta
XP_001086830
584
64481
T247
E
A
P
E
D
T
S
T
G
G
L
N
Q
D
S
Dog
Lupus familis
XP_536109
584
64640
S247
E
A
S
E
D
S
N
S
R
G
L
N
P
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61211
570
62811
G244
P
S
Q
D
S
L
D
G
K
P
L
Q
E
Q
M
Rat
Rattus norvegicus
Q5PPG7
570
62651
G244
L
S
Q
D
S
V
D
G
K
P
L
Q
E
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006322
315
34256
Q37
F
P
G
L
S
A
E
Q
L
V
E
L
I
P
N
Frog
Xenopus laevis
NP_001090591
583
64871
E244
E
D
P
E
E
Q
F
E
N
A
E
E
Q
L
K
Zebra Danio
Brachydanio rerio
NP_957456
590
66065
G250
E
S
V
E
D
K
E
G
E
N
I
D
G
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477481
563
61913
A247
L
T
L
E
S
Q
E
A
P
E
S
D
E
E
A
Honey Bee
Apis mellifera
XP_392122
528
58787
A231
E
E
C
A
K
T
I
A
T
D
E
I
E
I
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177291
597
65656
T263
D
D
V
C
A
T
E
T
N
T
D
K
Q
I
T
Baker's Yeast
Sacchar. cerevisiae
Q04600
565
63973
V236
E
V
L
D
H
F
T
V
S
D
V
D
Y
F
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.4
97.5
87.5
N.A.
80.9
81.1
N.A.
N.A.
33
58.7
56.9
N.A.
35.6
35
N.A.
N.A.
Protein Similarity:
100
84.9
98.6
93.6
N.A.
88.8
89.3
N.A.
N.A.
43.3
74.3
74.4
N.A.
51.3
55.6
N.A.
N.A.
P-Site Identity:
100
100
93.3
60
N.A.
6.6
6.6
N.A.
N.A.
0
26.6
20
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
100
93.3
80
N.A.
33.3
33.3
N.A.
N.A.
6.6
33.3
46.6
N.A.
33.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.3
26.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.4
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
0
8
8
8
0
16
0
8
0
0
0
0
8
% A
% Cys:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
16
0
24
39
0
16
0
0
16
8
24
0
31
0
% D
% Glu:
62
8
0
54
8
0
31
8
8
8
24
8
31
16
8
% E
% Phe:
8
0
0
0
0
8
8
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
8
0
0
0
0
24
8
31
0
0
8
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
8
8
8
16
8
% I
% Lys:
0
0
0
0
8
8
0
0
16
0
0
8
0
0
8
% K
% Leu:
16
0
16
8
0
8
0
0
8
0
47
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% M
% Asn:
0
0
0
0
0
0
8
0
16
8
0
31
0
0
8
% N
% Pro:
8
8
31
0
0
0
0
0
8
16
0
0
8
8
8
% P
% Gln:
0
0
16
0
0
16
0
8
0
0
0
16
39
16
0
% Q
% Arg:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% R
% Ser:
0
24
8
0
31
8
24
8
8
0
8
0
0
0
24
% S
% Thr:
0
8
0
0
0
39
8
31
8
8
0
0
0
0
16
% T
% Val:
0
8
16
0
0
8
0
8
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _