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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LGTN All Species: 27.88
Human Site: T27 Identified Species: 51.11
UniProt: P41214 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41214 NP_008824.2 584 64706 T27 R K L R A D V T T A F P T L G
Chimpanzee Pan troglodytes XP_514150 683 75708 T126 R K L R A D V T T T F P T L G
Rhesus Macaque Macaca mulatta XP_001086830 584 64481 T27 R K L R A D V T T A F P T L G
Dog Lupus familis XP_536109 584 64640 A27 R R L R A D V A A A F P G L G
Cat Felis silvestris
Mouse Mus musculus Q61211 570 62811 T27 R K L R A D V T A A F P A L G
Rat Rattus norvegicus Q5PPG7 570 62651 T27 R K L R A D V T V A F P T L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006322 315 34256
Frog Xenopus laevis NP_001090591 583 64871 S27 R K L R A D I S S A F P P L T
Zebra Danio Brachydanio rerio NP_957456 590 66065 S27 R K L R A D I S A A F P S L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477481 563 61913 E27 K K F R Q R V E A A F P H V S
Honey Bee Apis mellifera XP_392122 528 58787 S27 K K L C E E I S A I Y P T L T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_177291 597 65656 R27 K K L R R T V R N R L P L L T
Baker's Yeast Sacchar. cerevisiae Q04600 565 63973 Q27 K K L L Q T F Q K Q T N N E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.4 97.5 87.5 N.A. 80.9 81.1 N.A. N.A. 33 58.7 56.9 N.A. 35.6 35 N.A. N.A.
Protein Similarity: 100 84.9 98.6 93.6 N.A. 88.8 89.3 N.A. N.A. 43.3 74.3 74.4 N.A. 51.3 55.6 N.A. N.A.
P-Site Identity: 100 93.3 100 73.3 N.A. 86.6 93.3 N.A. N.A. 0 66.6 66.6 N.A. 40 33.3 N.A. N.A.
P-Site Similarity: 100 93.3 100 80 N.A. 86.6 93.3 N.A. N.A. 0 86.6 86.6 N.A. 53.3 66.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32.3 26.2 N.A.
Protein Similarity: N.A. N.A. N.A. 52.4 45.3 N.A.
P-Site Identity: N.A. N.A. N.A. 40 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 62 0 0 8 39 62 0 0 8 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 62 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 8 8 0 8 0 0 0 0 0 8 8 % E
% Phe: 0 0 8 0 0 0 8 0 0 0 70 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 47 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 24 0 0 8 0 0 0 0 0 % I
% Lys: 31 85 0 0 0 0 0 0 8 0 0 0 0 0 0 % K
% Leu: 0 0 85 8 0 0 0 0 0 0 8 0 8 77 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 8 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 85 8 0 0 % P
% Gln: 0 0 0 0 16 0 0 8 0 8 0 0 0 0 0 % Q
% Arg: 62 8 0 77 8 8 0 8 0 8 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 24 8 0 0 0 8 0 16 % S
% Thr: 0 0 0 0 0 16 0 39 24 8 8 0 39 0 24 % T
% Val: 0 0 0 0 0 0 62 0 8 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _