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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRPH All Species: 21.82
Human Site: S42 Identified Species: 60
UniProt: P41219 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41219 NP_006253.2 470 53651 S42 S S S S R F S S S R L L G S A
Chimpanzee Pan troglodytes Q5R1W8 466 53634 T48 G S A L R P S T S R S L Y A S
Rhesus Macaque Macaca mulatta XP_001108977 470 53605 S42 S S S S R F S S S R L L G S A
Dog Lupus familis XP_534812 469 53365 G46 F S S S R L L G S A S P G S S
Cat Felis silvestris
Mouse Mus musculus P15331 475 54249 S49 S S S S R F S S S R L L G S G
Rat Rattus norvegicus P21807 468 53531 S42 S S S S R F S S S R L L G S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P02542 463 53261 Y44 S S V T S R V Y Q V S R T S A
Frog Xenopus laevis P48676 456 51977 S51 G P S S R S S S S A F R V R S
Zebra Danio Brachydanio rerio Q58EE9 444 51231 T44 H S S P R H L T S S P L T L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 55.7 99.7 97 N.A. 94.3 95.9 N.A. N.A. 57.6 70.2 54.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 75.5 100 98.5 N.A. 96.4 97.4 N.A. N.A. 76.5 83.4 72.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 40 100 46.6 N.A. 93.3 93.3 N.A. N.A. 26.6 40 33.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 66.6 100 53.3 N.A. 93.3 93.3 N.A. N.A. 33.3 46.6 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 0 0 0 0 23 0 0 0 12 34 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 12 0 0 0 0 45 0 0 0 0 12 0 0 0 0 % F
% Gly: 23 0 0 0 0 0 0 12 0 0 0 0 56 0 23 % G
% His: 12 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 12 0 12 23 0 0 0 45 67 0 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 12 0 12 0 12 0 0 0 0 12 12 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 89 12 0 0 0 56 0 23 0 12 0 % R
% Ser: 56 89 78 67 12 12 67 56 89 12 34 0 0 67 45 % S
% Thr: 0 0 0 12 0 0 0 23 0 0 0 0 23 0 0 % T
% Val: 0 0 12 0 0 0 12 0 0 12 0 0 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 12 0 0 0 0 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _