KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS2
All Species:
27.88
Human Site:
S124
Identified Species:
68.15
UniProt:
P41220
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41220
NP_002914.1
211
24382
S124
E
D
F
K
K
T
K
S
P
Q
K
L
S
S
K
Chimpanzee
Pan troglodytes
XP_525006
211
24375
S124
E
D
F
K
K
T
K
S
P
Q
K
L
S
S
K
Rhesus Macaque
Macaca mulatta
XP_001112788
211
24336
S124
E
D
F
K
K
T
K
S
P
Q
K
L
S
S
K
Dog
Lupus familis
XP_545701
285
32882
S198
E
D
F
K
K
T
K
S
P
Q
K
L
S
S
K
Cat
Felis silvestris
Mouse
Mus musculus
O08849
211
24275
S124
E
D
F
K
K
T
K
S
P
Q
K
L
S
S
K
Rat
Rattus norvegicus
Q9JHX0
211
24304
S124
E
D
F
K
K
T
K
S
P
Q
K
L
S
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516481
781
86989
S421
E
D
F
K
N
T
K
S
P
Q
K
M
T
S
K
Chicken
Gallus gallus
Q7SZC6
208
23504
A123
D
E
F
I
S
V
Q
A
T
K
E
V
N
L
D
Frog
Xenopus laevis
A1A643
201
23280
S117
D
Y
K
A
T
N
D
S
E
E
L
R
C
K
A
Zebra Danio
Brachydanio rerio
Q6DGI0
174
20503
K90
K
K
I
K
S
P
A
K
M
M
S
K
A
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.5
68.4
N.A.
96.2
96.6
N.A.
22
41.7
37.4
40.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
99.5
70.5
N.A.
97.6
97.6
N.A.
25.6
59.7
53.5
56.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
80
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
60
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
10
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
20
70
0
0
0
0
10
0
0
0
0
0
0
0
10
% D
% Glu:
70
10
0
0
0
0
0
0
10
10
10
0
0
0
0
% E
% Phe:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
10
80
60
0
70
10
0
10
70
10
0
10
80
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
10
60
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
10
10
0
10
0
0
0
% M
% Asn:
0
0
0
0
10
10
0
0
0
0
0
0
10
10
0
% N
% Pro:
0
0
0
0
0
10
0
0
70
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
70
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
0
20
0
0
80
0
0
10
0
60
70
0
% S
% Thr:
0
0
0
0
10
70
0
0
10
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _