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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT5A
All Species:
14.85
Human Site:
S289
Identified Species:
29.7
UniProt:
P41221
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41221
NP_003383.2
380
42339
S289
G
K
L
V
Q
V
N
S
R
F
N
S
P
T
T
Chimpanzee
Pan troglodytes
Q2QLE7
360
40426
F271
T
K
N
D
L
V
Y
F
E
N
S
P
D
Y
C
Rhesus Macaque
Macaca mulatta
XP_001101962
380
42363
S289
G
K
L
V
Q
V
N
S
R
F
N
A
P
T
T
Dog
Lupus familis
XP_541837
360
40483
F271
L
V
Q
V
N
S
R
F
N
S
P
T
T
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
P22725
380
42291
S289
G
K
L
V
Q
V
N
S
R
F
N
S
P
T
T
Rat
Rattus norvegicus
Q9QXQ7
380
42265
S289
G
K
L
V
Q
V
N
S
R
F
N
S
P
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
Y271
P
T
K
N
D
L
V
Y
F
E
N
S
P
D
Y
Chicken
Gallus gallus
Q98SN7
385
42934
K283
T
G
F
T
V
A
N
K
N
F
R
K
P
T
K
Frog
Xenopus laevis
P31286
380
42501
N289
G
K
L
V
Q
V
N
N
K
F
N
S
P
T
M
Zebra Danio
Brachydanio rerio
Q92050
363
41119
N272
G
K
L
E
L
V
N
N
R
F
N
P
P
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397473
422
46971
P331
G
R
L
S
M
R
D
P
R
F
S
L
P
T
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779946
415
46408
A324
G
R
L
V
N
S
D
A
R
F
N
K
P
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.7
98.9
94.4
N.A.
98.6
98.4
N.A.
46.5
48.8
85.5
78.1
N.A.
N.A.
51.9
N.A.
56.1
Protein Similarity:
100
60.5
99.7
94.7
N.A.
98.9
98.9
N.A.
61.5
62.3
91.8
86.8
N.A.
N.A.
67.3
N.A.
69.4
P-Site Identity:
100
13.3
93.3
6.6
N.A.
100
100
N.A.
20
26.6
80
66.6
N.A.
N.A.
40
N.A.
53.3
P-Site Similarity:
100
20
100
13.3
N.A.
100
100
N.A.
26.6
26.6
93.3
73.3
N.A.
N.A.
60
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
9
0
0
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
9
9
0
17
0
0
0
0
0
9
9
9
% D
% Glu:
0
0
0
9
0
0
0
0
9
9
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
17
9
75
0
0
0
0
0
% F
% Gly:
67
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
59
9
0
0
0
0
9
9
0
0
17
0
0
9
% K
% Leu:
9
0
67
0
17
9
0
0
0
0
0
9
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
9
9
17
0
59
17
17
9
67
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
9
0
0
9
17
84
0
0
% P
% Gln:
0
0
9
0
42
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
17
0
0
0
9
9
0
59
0
9
0
0
0
9
% R
% Ser:
0
0
0
9
0
17
0
34
0
9
17
42
0
0
0
% S
% Thr:
17
9
0
9
0
0
0
0
0
0
0
9
9
75
34
% T
% Val:
0
9
0
59
9
59
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
9
0
0
0
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _