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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT5A
All Species:
20.61
Human Site:
Y231
Identified Species:
41.21
UniProt:
P41221
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41221
NP_003383.2
380
42339
Y231
E
A
G
R
R
T
V
Y
N
L
A
D
V
A
C
Chimpanzee
Pan troglodytes
Q2QLE7
360
40426
L217
G
V
S
G
S
C
T
L
R
T
C
W
L
A
M
Rhesus Macaque
Macaca mulatta
XP_001101962
380
42363
Y231
E
A
G
R
R
T
V
Y
N
L
A
D
V
A
C
Dog
Lupus familis
XP_541837
360
40483
A217
V
Y
N
L
A
D
V
A
C
K
C
H
G
V
S
Cat
Felis silvestris
Mouse
Mus musculus
P22725
380
42291
Y231
E
A
G
R
R
T
V
Y
N
L
A
D
V
A
C
Rat
Rattus norvegicus
Q9QXQ7
380
42265
Y231
E
A
G
R
R
T
V
Y
N
L
A
D
V
A
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
T217
H
G
V
S
G
S
C
T
L
R
T
C
W
L
A
Chicken
Gallus gallus
Q98SN7
385
42934
K224
R
C
G
R
M
A
V
K
R
F
L
K
L
E
C
Frog
Xenopus laevis
P31286
380
42501
S231
E
A
G
R
R
A
V
S
T
L
A
D
V
A
C
Zebra Danio
Brachydanio rerio
Q92050
363
41119
A217
R
M
A
V
Y
N
L
A
N
V
A
C
K
C
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397473
422
46971
I273
E
A
G
R
R
A
V
I
K
R
S
K
V
T
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779946
415
46408
Y266
E
A
G
R
K
A
V
Y
D
N
A
G
T
E
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.7
98.9
94.4
N.A.
98.6
98.4
N.A.
46.5
48.8
85.5
78.1
N.A.
N.A.
51.9
N.A.
56.1
Protein Similarity:
100
60.5
99.7
94.7
N.A.
98.9
98.9
N.A.
61.5
62.3
91.8
86.8
N.A.
N.A.
67.3
N.A.
69.4
P-Site Identity:
100
6.6
100
6.6
N.A.
100
100
N.A.
0
26.6
80
13.3
N.A.
N.A.
53.3
N.A.
53.3
P-Site Similarity:
100
13.3
100
6.6
N.A.
100
100
N.A.
6.6
33.3
80
26.6
N.A.
N.A.
60
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
59
9
0
9
34
0
17
0
0
59
0
0
50
9
% A
% Cys:
0
9
0
0
0
9
9
0
9
0
17
17
0
9
67
% C
% Asp:
0
0
0
0
0
9
0
0
9
0
0
42
0
0
0
% D
% Glu:
59
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
9
9
67
9
9
0
0
0
0
0
0
9
9
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
9
0
0
9
9
9
0
17
9
0
0
% K
% Leu:
0
0
0
9
0
0
9
9
9
42
9
0
17
9
0
% L
% Met:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
9
0
0
9
0
0
42
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
17
0
0
67
50
0
0
0
17
17
0
0
0
0
0
% R
% Ser:
0
0
9
9
9
9
0
9
0
0
9
0
0
0
9
% S
% Thr:
0
0
0
0
0
34
9
9
9
9
9
0
9
9
0
% T
% Val:
9
9
9
9
0
0
75
0
0
9
0
0
50
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% W
% Tyr:
0
9
0
0
9
0
0
42
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _