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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTGDS All Species: 13.03
Human Site: S119 Identified Species: 28.67
UniProt: P41222 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41222 NP_000945.3 190 21029 S119 W G S T Y S V S V V E T D Y D
Chimpanzee Pan troglodytes XP_001168528 325 34672 S174 A D A G G G R S P Q F L G R W
Rhesus Macaque Macaca mulatta XP_001091839 190 20992 S119 W G S T Y S V S V V E T D Y D
Dog Lupus familis XP_548441 198 22874 V128 P G V Q S Y L V Q V V A T N Y
Cat Felis silvestris
Mouse Mus musculus O09114 189 21048 S119 S G S I H S V S V V E A N Y D
Rat Rattus norvegicus P22057 189 21283 S119 W G S F H S L S V V E T D Y D
Wallaby Macropus eugenll Q29614 174 20201 A104 I Y I S S E S A S Y T F S V M
Platypus Ornith. anatinus XP_001516011 215 23425 W145 F Y Y K S L R W G S D H D V R
Chicken Gallus gallus NP_989590 185 20825 R114 W G S N H D I R V V E T N Y D
Frog Xenopus laevis NP_001081513 184 20909 R114 Y G S E H D M R V V E T N Y D
Zebra Danio Brachydanio rerio NP_998799 184 20887 M113 R W G N D N D M R V V D A K F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.1 94.2 37.3 N.A. 71.5 68.4 21.5 30.7 43.1 40 30 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 53.5 95.7 53.5 N.A. 83.6 80.5 38.9 47.9 60 63.6 50.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 13.3 N.A. 66.6 80 0 6.6 60 53.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 100 20 N.A. 80 93.3 13.3 20 80 80 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 0 0 10 0 0 0 19 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 10 19 10 0 0 0 10 10 37 0 55 % D
% Glu: 0 0 0 10 0 10 0 0 0 0 55 0 0 0 0 % E
% Phe: 10 0 0 10 0 0 0 0 0 0 10 10 0 0 10 % F
% Gly: 0 64 10 10 10 10 0 0 10 0 0 0 10 0 0 % G
% His: 0 0 0 0 37 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 10 0 10 10 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 0 0 0 10 19 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 19 0 10 0 0 0 0 0 0 28 10 0 % N
% Pro: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 10 10 0 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 19 19 10 0 0 0 0 10 10 % R
% Ser: 10 0 55 10 28 37 10 46 10 10 0 0 10 0 0 % S
% Thr: 0 0 0 19 0 0 0 0 0 0 10 46 10 0 0 % T
% Val: 0 0 10 0 0 0 28 10 55 73 19 0 0 19 0 % V
% Trp: 37 10 0 0 0 0 0 10 0 0 0 0 0 0 10 % W
% Tyr: 10 19 10 0 19 10 0 0 0 10 0 0 0 55 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _