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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTGDS
All Species:
17.27
Human Site:
Y149
Identified Species:
38
UniProt:
P41222
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41222
NP_000945.3
190
21029
Y149
D
F
R
M
A
T
L
Y
S
R
T
Q
T
P
R
Chimpanzee
Pan troglodytes
XP_001168528
325
34672
K204
K
A
A
L
S
M
C
K
S
V
V
A
P
A
A
Rhesus Macaque
Macaca mulatta
XP_001091839
190
20992
Y149
D
F
R
M
A
T
L
Y
S
R
T
Q
T
P
R
Dog
Lupus familis
XP_548441
198
22874
Y158
E
Y
F
K
I
T
L
Y
G
R
T
K
E
L
P
Cat
Felis silvestris
Mouse
Mus musculus
O09114
189
21048
Y149
D
F
R
M
A
T
L
Y
S
R
T
Q
T
L
K
Rat
Rattus norvegicus
P22057
189
21283
Y149
D
F
R
M
A
T
L
Y
S
R
A
Q
L
L
K
Wallaby
Macropus eugenll
Q29614
174
20201
C134
S
D
R
E
K
M
A
C
A
H
Y
V
R
R
I
Platypus
Ornith. anatinus
XP_001516011
215
23425
F175
K
S
K
G
S
G
N
F
N
M
A
V
L
Y
G
Chicken
Gallus gallus
NP_989590
185
20825
S144
S
N
M
V
L
L
Y
S
R
T
K
E
V
A
P
Frog
Xenopus laevis
NP_001081513
184
20909
G144
N
Q
I
V
S
L
F
G
R
D
K
D
L
R
P
Zebra Danio
Brachydanio rerio
NP_998799
184
20887
Y143
S
E
I
L
N
K
L
Y
S
R
T
P
E
M
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.1
94.2
37.3
N.A.
71.5
68.4
21.5
30.7
43.1
40
30
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
53.5
95.7
53.5
N.A.
83.6
80.5
38.9
47.9
60
63.6
50.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
33.3
N.A.
86.6
73.3
6.6
0
0
0
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
53.3
N.A.
93.3
80
13.3
26.6
13.3
20
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
37
0
10
0
10
0
19
10
0
19
10
% A
% Cys:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% C
% Asp:
37
10
0
0
0
0
0
0
0
10
0
10
0
0
0
% D
% Glu:
10
10
0
10
0
0
0
0
0
0
0
10
19
0
0
% E
% Phe:
0
37
10
0
0
0
10
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
10
0
10
10
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
19
0
10
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
19
0
10
10
10
10
0
10
0
0
19
10
0
0
19
% K
% Leu:
0
0
0
19
10
19
55
0
0
0
0
0
28
28
0
% L
% Met:
0
0
10
37
0
19
0
0
0
10
0
0
0
10
0
% M
% Asn:
10
10
0
0
10
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
10
19
28
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
37
0
0
0
% Q
% Arg:
0
0
46
0
0
0
0
0
19
55
0
0
10
19
19
% R
% Ser:
28
10
0
0
28
0
0
10
55
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
46
0
0
0
10
46
0
28
0
0
% T
% Val:
0
0
0
19
0
0
0
0
0
10
10
19
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
10
55
0
0
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _