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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOX3 All Species: 8.48
Human Site: S110 Identified Species: 20.74
UniProt: P41225 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41225 NP_005625.2 446 45210 S110 P G G A G K S S A N A A G G A
Chimpanzee Pan troglodytes XP_516895 690 75569 P153 T E L K P P G P Q Q T S G G G
Rhesus Macaque Macaca mulatta XP_001085170 446 45124 S110 P G G A G K S S A N A A G G A
Dog Lupus familis XP_852934 444 44718 S110 A G G A G K S S A T A A G G A
Cat Felis silvestris
Mouse Mus musculus P53784 375 37839 G57 G G A N G G G G G G G G G G S
Rat Rattus norvegicus XP_001054955 575 59634 P140 P R N A F N V P S M P G L L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506984 290 31501
Chicken Gallus gallus P48433 312 34438
Frog Xenopus laevis P55863 309 34016
Zebra Danio Brachydanio rerio Q6EJB7 300 33398
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32.6 98.6 91.6 N.A. 77.1 34.4 N.A. 43.5 54.9 53.3 52.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 40.4 99.5 93.9 N.A. 78.4 44.5 N.A. 50.9 58.2 59.1 58.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 86.6 N.A. 26.6 13.3 N.A. 0 0 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 86.6 N.A. 33.3 20 N.A. 0 0 0 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 40 0 0 0 0 30 0 30 30 0 0 30 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 40 30 0 40 10 20 10 10 10 10 20 50 50 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 30 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 0 0 0 0 0 0 0 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 10 10 0 10 0 0 0 20 0 0 0 0 0 % N
% Pro: 30 0 0 0 10 10 0 20 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 30 30 10 0 0 10 0 0 10 % S
% Thr: 10 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % T
% Val: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _