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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOX3
All Species:
15.76
Human Site:
T214
Identified Species:
38.52
UniProt:
P41225
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41225
NP_005625.2
446
45210
T214
K
Y
R
P
R
R
K
T
K
T
L
L
K
K
D
Chimpanzee
Pan troglodytes
XP_516895
690
75569
T257
K
Y
R
P
R
R
K
T
K
T
L
M
K
K
D
Rhesus Macaque
Macaca mulatta
XP_001085170
446
45124
T214
K
Y
R
P
R
R
K
T
K
T
L
L
K
K
D
Dog
Lupus familis
XP_852934
444
44718
T214
K
Y
R
P
R
R
K
T
K
T
L
L
K
K
D
Cat
Felis silvestris
Mouse
Mus musculus
P53784
375
37839
D151
T
K
T
L
L
K
K
D
K
Y
S
L
P
G
G
Rat
Rattus norvegicus
XP_001054955
575
59634
L322
Y
S
L
L
E
T
E
L
K
N
P
V
G
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506984
290
31501
E66
E
K
R
P
F
I
D
E
A
K
R
L
R
A
L
Chicken
Gallus gallus
P48433
312
34438
S88
G
A
D
W
K
L
L
S
D
A
E
K
R
P
F
Frog
Xenopus laevis
P55863
309
34016
S84
D
W
K
L
L
S
D
S
D
K
R
P
F
I
D
Zebra Danio
Brachydanio rerio
Q6EJB7
300
33398
L75
R
L
G
A
D
W
K
L
L
T
D
A
E
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.6
98.6
91.6
N.A.
77.1
34.4
N.A.
43.5
54.9
53.3
52.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
40.4
99.5
93.9
N.A.
78.4
44.5
N.A.
50.9
58.2
59.1
58.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
20
6.6
N.A.
20
0
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
20
N.A.
33.3
20
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
0
10
10
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
10
0
20
10
20
0
10
0
0
0
50
% D
% Glu:
10
0
0
0
10
0
10
10
0
0
10
0
10
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
10
% F
% Gly:
10
0
10
0
0
0
0
0
0
0
0
0
10
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% I
% Lys:
40
20
10
0
10
10
60
0
60
20
0
10
40
50
0
% K
% Leu:
0
10
10
30
20
10
10
20
10
0
40
50
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
50
0
0
0
0
0
0
10
10
10
20
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
50
0
40
40
0
0
0
0
20
0
20
0
10
% R
% Ser:
0
10
0
0
0
10
0
20
0
0
10
0
0
0
0
% S
% Thr:
10
0
10
0
0
10
0
40
0
50
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
10
0
10
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
40
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _