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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P2RY2
All Species:
22.12
Human Site:
S359
Identified Species:
54.07
UniProt:
P41231
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41231
NP_002555.2
377
42290
S359
V
L
G
S
S
E
D
S
R
R
T
E
S
T
P
Chimpanzee
Pan troglodytes
XP_522101
377
42271
S359
V
L
G
S
S
E
D
S
R
R
T
E
S
T
P
Rhesus Macaque
Macaca mulatta
XP_001115229
377
42322
S359
V
L
G
S
S
E
D
S
R
R
T
E
S
T
P
Dog
Lupus familis
XP_542321
377
42380
S359
V
S
T
S
S
E
D
S
R
R
T
E
S
T
P
Cat
Felis silvestris
Mouse
Mus musculus
P35383
373
42156
S356
L
S
V
S
S
D
D
S
R
R
T
E
S
T
P
Rat
Rattus norvegicus
P41232
374
42119
S357
L
S
I
S
S
D
D
S
R
R
T
E
S
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518271
346
38599
G329
D
P
T
L
T
L
Q
G
Q
G
S
P
S
P
A
Chicken
Gallus gallus
P34996
362
41176
E345
N
V
Q
S
K
S
E
E
M
T
L
N
I
L
T
Frog
Xenopus laevis
P79928
537
62006
N409
R
R
S
T
I
K
R
N
S
T
D
K
N
D
M
Zebra Danio
Brachydanio rerio
A5PLE7
368
41686
S351
N
D
K
I
Q
M
N
S
R
S
F
Q
K
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
97
89.6
N.A.
90.1
88.3
N.A.
64.1
37.9
37.2
29.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98.9
93.6
N.A.
94.4
92.8
N.A.
71.8
55.1
49.1
46.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
73.3
73.3
N.A.
6.6
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
26.6
20
33.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
20
60
0
0
0
10
0
0
10
0
% D
% Glu:
0
0
0
0
0
40
10
10
0
0
0
60
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
30
0
0
0
0
10
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
10
10
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
10
0
10
10
0
0
0
0
0
10
10
0
0
% K
% Leu:
20
30
0
10
0
10
0
0
0
0
10
0
0
10
0
% L
% Met:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
10
% M
% Asn:
20
0
0
0
0
0
10
10
0
0
0
10
10
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
10
0
10
60
% P
% Gln:
0
0
10
0
10
0
10
0
10
0
0
10
0
0
0
% Q
% Arg:
10
10
0
0
0
0
10
0
70
60
0
0
0
0
10
% R
% Ser:
0
30
10
70
60
10
0
70
10
10
10
0
70
0
0
% S
% Thr:
0
0
20
10
10
0
0
0
0
20
60
0
0
60
10
% T
% Val:
40
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _