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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP1R2 All Species: 30.91
Human Site: Y63 Identified Species: 75.56
UniProt: P41236 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41236 NP_006232.1 205 23015 Y63 Y H P A D K D Y G L M K I D E
Chimpanzee Pan troglodytes XP_516963 205 23027 Y63 Y H P A D K D Y G L M K I D E
Rhesus Macaque Macaca mulatta XP_001097826 205 22972 Y63 Y H P A D K D Y G L M K I D E
Dog Lupus familis XP_548958 208 22793 Y63 H R R A Y R D Y D L M K I N E
Cat Felis silvestris
Mouse Mus musculus Q9DCL8 206 23101 Y64 Y H P A D K D Y G L M K I D E
Rat Rattus norvegicus P50411 205 23053 Y63 Y H P A D K D Y G L M K I D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511436 176 19998 S45 L M K I D E P S T P Y H S M I
Chicken Gallus gallus NP_001026484 237 26006 Y75 Y H P A G K D Y G L M K I D E
Frog Xenopus laevis NP_001091136 188 21452 P57 N I L A T Y H P S D K D Y G L
Zebra Danio Brachydanio rerio NP_991231 204 22948 Y64 Y H P A D K D Y G L M K I D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.5 50 N.A. 83.9 84.8 N.A. 58 54.4 57.5 56 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 99.5 67.3 N.A. 90.2 91.2 N.A. 68.2 65.4 70.7 71.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 53.3 N.A. 100 100 N.A. 6.6 93.3 6.6 100 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 73.3 N.A. 100 100 N.A. 13.3 93.3 6.6 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 90 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 70 0 80 0 10 10 0 10 0 70 0 % D
% Glu: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 80 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 0 70 0 0 0 0 10 0 % G
% His: 10 70 0 0 0 0 10 0 0 0 0 10 0 0 0 % H
% Ile: 0 10 0 10 0 0 0 0 0 0 0 0 80 0 10 % I
% Lys: 0 0 10 0 0 70 0 0 0 0 10 80 0 0 0 % K
% Leu: 10 0 10 0 0 0 0 0 0 80 0 0 0 0 10 % L
% Met: 0 10 0 0 0 0 0 0 0 0 80 0 0 10 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 70 0 0 0 10 10 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 10 0 0 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 10 10 0 0 0 10 0 0 % S
% Thr: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 70 0 0 0 10 10 0 80 0 0 10 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _