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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA4
All Species:
33.94
Human Site:
S127
Identified Species:
74.67
UniProt:
P41247
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41247
NP_001135861.1
253
27980
S127
T
R
E
N
H
L
V
S
T
F
S
S
R
E
D
Chimpanzee
Pan troglodytes
XP_529255
253
27946
S127
T
R
E
N
H
L
V
S
T
F
S
S
R
E
D
Rhesus Macaque
Macaca mulatta
XP_001089320
253
27997
S127
T
R
E
N
H
L
V
S
T
F
S
S
R
E
D
Dog
Lupus familis
XP_548849
669
71727
S543
T
R
E
N
Y
L
V
S
S
F
S
S
R
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJ56
486
53638
S130
D
G
E
N
V
I
I
S
H
F
S
S
K
D
E
Rat
Rattus norvegicus
P0C548
478
52548
S130
D
G
E
N
V
I
I
S
H
F
S
S
K
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509841
390
42660
S130
D
G
K
N
V
L
V
S
H
F
C
S
K
Q
D
Chicken
Gallus gallus
NP_001124212
253
28332
S127
N
G
K
N
Y
L
F
S
N
F
A
S
R
E
D
Frog
Xenopus laevis
NP_001088835
255
28503
S127
S
R
K
N
C
L
V
S
H
F
A
S
R
E
E
Zebra Danio
Brachydanio rerio
NP_001002338
473
52215
S130
D
G
Q
N
V
L
V
S
D
F
S
S
K
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_505749
266
29603
K143
W
E
N
I
M
I
N
K
F
D
S
R
D
H
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.8
34.9
N.A.
21.6
20.7
N.A.
25.3
76.6
65.8
24.1
N.A.
N.A.
N.A.
39.4
N.A.
Protein Similarity:
100
99.5
98.8
36.6
N.A.
32.7
33.8
N.A.
38.7
88.1
83.1
35.7
N.A.
N.A.
N.A.
55.6
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
40
40
N.A.
46.6
53.3
60
53.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
73.3
73.3
N.A.
66.6
73.3
86.6
73.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
37
0
0
0
0
0
0
0
10
10
0
0
10
19
55
% D
% Glu:
0
10
55
0
0
0
0
0
0
0
0
0
0
64
37
% E
% Phe:
0
0
0
0
0
0
10
0
10
91
0
0
0
0
0
% F
% Gly:
0
46
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
28
0
0
0
37
0
0
0
0
10
0
% H
% Ile:
0
0
0
10
0
28
19
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
28
0
0
0
0
10
0
0
0
0
37
0
0
% K
% Leu:
0
0
0
0
0
73
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
91
0
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
46
0
0
0
0
0
0
0
0
0
10
55
0
0
% R
% Ser:
10
0
0
0
0
0
0
91
10
0
73
91
0
0
0
% S
% Thr:
37
0
0
0
0
0
0
0
28
0
0
0
0
0
0
% T
% Val:
0
0
0
0
37
0
64
0
0
0
0
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _