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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GARS All Species: 51.82
Human Site: S192 Identified Species: 76
UniProt: P41250 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41250 NP_002038.2 739 83140 S192 P E P V L K T S G H V D K F A
Chimpanzee Pan troglodytes XP_519025 739 83175 S192 P E P V L K T S G H V D K F A
Rhesus Macaque Macaca mulatta XP_001086099 606 68263 R100 A V A E L K A R K R V L E A K
Dog Lupus familis XP_532502 749 83638 S194 P E P V L K T S G H V D K F A
Cat Felis silvestris
Mouse Mus musculus Q9CZD3 729 81859 S182 P E P V L K T S G H V D K F A
Rat Rattus norvegicus Q5I0G4 637 72012 L123 L K A H L Q K L M S D K K C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521270 751 83825 S222 P E P V L K T S G H V D K F A
Chicken Gallus gallus NP_001026681 685 77562 S138 P E P V L K T S G H V D K F A
Frog Xenopus laevis NP_001089920 740 83613 S193 P E P V L K T S G H V D K F A
Zebra Danio Brachydanio rerio XP_692410 764 86292 S217 P E P V L K T S G H V D K F A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730022 765 85173 S224 P E P V L K A S G H V E R F A
Honey Bee Apis mellifera XP_391940 740 84354 S198 P E P V L E A S G H V E R F A
Nematode Worm Caenorhab. elegans Q10039 742 84131 S202 P E P V L K A S G H V D R F A
Sea Urchin Strong. purpuratus XP_784166 684 77193 S143 P E N V F K A S G H V E R F A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23627 729 81925 S188 P E V V L K A S G H V D K F T
Baker's Yeast Sacchar. cerevisiae P38088 667 75392 D134 E A R G L V E D A N A A A K D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 77.5 92.5 N.A. 91.6 82.2 N.A. 77.6 83.6 82.9 80.3 N.A. 55.8 58.6 53.9 56.9
Protein Similarity: 100 99.7 79.4 95.7 N.A. 95.6 85.2 N.A. 86.4 90.1 90.6 87.8 N.A. 70.8 74.7 70.8 72.8
P-Site Identity: 100 100 20 100 N.A. 100 13.3 N.A. 100 100 100 100 N.A. 80 73.3 86.6 66.6
P-Site Similarity: 100 100 26.6 100 N.A. 100 33.3 N.A. 100 100 100 100 N.A. 93.3 93.3 93.3 80
Percent
Protein Identity: N.A. N.A. N.A. 45 38.4 N.A.
Protein Similarity: N.A. N.A. N.A. 61.9 55.3 N.A.
P-Site Identity: N.A. N.A. N.A. 80 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 13 0 0 0 38 0 7 0 7 7 7 7 75 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 0 0 0 0 0 0 7 0 0 7 63 0 0 7 % D
% Glu: 7 82 0 7 0 7 7 0 0 0 0 19 7 0 0 % E
% Phe: 0 0 0 0 7 0 0 0 0 0 0 0 0 82 0 % F
% Gly: 0 0 0 7 0 0 0 0 82 0 0 0 0 0 0 % G
% His: 0 0 0 7 0 0 0 0 0 82 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 7 0 0 0 82 7 0 7 0 0 7 63 7 7 % K
% Leu: 7 0 0 0 94 0 0 7 0 0 0 7 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % N
% Pro: 82 0 69 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 7 0 0 0 0 7 0 7 0 0 25 0 0 % R
% Ser: 0 0 0 0 0 0 0 82 0 7 0 0 0 0 7 % S
% Thr: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 7 % T
% Val: 0 7 7 82 0 7 0 0 0 0 88 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _