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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GARS All Species: 43.64
Human Site: S265 Identified Species: 64
UniProt: P41250 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41250 NP_002038.2 739 83140 S265 F V N Y N V K S P I T G N D L
Chimpanzee Pan troglodytes XP_519025 739 83175 S265 F V N Y N V K S P I T G N D L
Rhesus Macaque Macaca mulatta XP_001086099 606 68263 G153 L Y D F G P V G C A L K N N I
Dog Lupus familis XP_532502 749 83638 S267 F V N Y N V K S P N T G N D L
Cat Felis silvestris
Mouse Mus musculus Q9CZD3 729 81859 S255 F V N Y N V K S P T T G N D L
Rat Rattus norvegicus Q5I0G4 637 72012 F176 D L S P P V P F N L M F Q T F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521270 751 83825 S295 F V N Y N V K S P I T G N D L
Chicken Gallus gallus NP_001026681 685 77562 S211 F V N Y N V K S P I T G N D L
Frog Xenopus laevis NP_001089920 740 83613 S266 F V K Y N V K S P I T L N D L
Zebra Danio Brachydanio rerio XP_692410 764 86292 S290 F V Q Y N V K S P S T G N D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730022 765 85173 S297 L A K Y N I K S P L T G N D L
Honey Bee Apis mellifera XP_391940 740 84354 S271 L S K F N I K S P I T G N D L
Nematode Worm Caenorhab. elegans Q10039 742 84131 S275 I T R F N F K S P I T G N D L
Sea Urchin Strong. purpuratus XP_784166 684 77193 S216 F R K Y Q V K S P T T N N D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23627 729 81925 A262 I R E Y G I T A P D T K N P L
Baker's Yeast Sacchar. cerevisiae P38088 667 75392 N194 M E K Y D I G N P V T G E T L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 77.5 92.5 N.A. 91.6 82.2 N.A. 77.6 83.6 82.9 80.3 N.A. 55.8 58.6 53.9 56.9
Protein Similarity: 100 99.7 79.4 95.7 N.A. 95.6 85.2 N.A. 86.4 90.1 90.6 87.8 N.A. 70.8 74.7 70.8 72.8
P-Site Identity: 100 100 6.6 93.3 N.A. 93.3 6.6 N.A. 100 100 86.6 86.6 N.A. 66.6 66.6 66.6 66.6
P-Site Similarity: 100 100 33.3 93.3 N.A. 93.3 26.6 N.A. 100 100 86.6 86.6 N.A. 80 80 73.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. 45 38.4 N.A.
Protein Similarity: N.A. N.A. N.A. 61.9 55.3 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 7 0 7 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 7 0 7 0 7 0 0 0 0 7 0 0 0 75 0 % D
% Glu: 0 7 7 0 0 0 0 0 0 0 0 0 7 0 0 % E
% Phe: 57 0 0 19 0 7 0 7 0 0 0 7 0 0 7 % F
% Gly: 0 0 0 0 13 0 7 7 0 0 0 69 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 13 0 0 0 0 25 0 0 0 44 0 0 0 0 7 % I
% Lys: 0 0 32 0 0 0 75 0 0 0 0 13 0 0 0 % K
% Leu: 19 7 0 0 0 0 0 0 0 13 7 7 0 0 88 % L
% Met: 7 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 38 0 69 0 0 7 7 7 0 7 88 7 0 % N
% Pro: 0 0 0 7 7 7 7 0 88 0 0 0 0 7 0 % P
% Gln: 0 0 7 0 7 0 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 13 7 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 7 7 0 0 0 0 75 0 7 0 0 0 0 0 % S
% Thr: 0 7 0 0 0 0 7 0 0 13 88 0 0 13 0 % T
% Val: 0 50 0 0 0 63 7 0 0 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 75 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _