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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GARS All Species: 12.73
Human Site: S53 Identified Species: 18.67
UniProt: P41250 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41250 NP_002038.2 739 83140 S53 L P A A A S R S S M D G A G A
Chimpanzee Pan troglodytes XP_519025 739 83175 S53 L P A A A S R S S M D G A G A
Rhesus Macaque Macaca mulatta XP_001086099 606 68263 P22 A L L L L L P P R L L A R P S
Dog Lupus familis XP_532502 749 83638 S55 P A A A A R S S S M D G A G A
Cat Felis silvestris
Mouse Mus musculus Q9CZD3 729 81859 S43 A P A Q P A A S R S S M D S A
Rat Rattus norvegicus Q5I0G4 637 72012 S43 F A I Y G G V S G L Y D F G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521270 751 83825 S72 D G V H R P F S D V E T E A Q
Chicken Gallus gallus NP_001026681 685 77562 A46 R A V A E L K A R K R V L E A
Frog Xenopus laevis NP_001089920 740 83613 P47 R P R Q H P R P T P L T R P D
Zebra Danio Brachydanio rerio XP_692410 764 86292 R55 L C G S S P T R V L S L S A H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730022 765 85173 T64 Q P Q Q P A A T T S W G T K K
Honey Bee Apis mellifera XP_391940 740 84354 I58 D R E V K I Q I L E D M S D P
Nematode Worm Caenorhab. elegans Q10039 742 84131 L74 T P E I E A K L A P L R A A V
Sea Urchin Strong. purpuratus XP_784166 684 77193 A55 E L K A R K K A L E E K E L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23627 729 81925 Q45 I P M D A T E Q S L R Q S L S
Baker's Yeast Sacchar. cerevisiae P38088 667 75392 N55 P P G C A F Q N N I I D A W R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 77.5 92.5 N.A. 91.6 82.2 N.A. 77.6 83.6 82.9 80.3 N.A. 55.8 58.6 53.9 56.9
Protein Similarity: 100 99.7 79.4 95.7 N.A. 95.6 85.2 N.A. 86.4 90.1 90.6 87.8 N.A. 70.8 74.7 70.8 72.8
P-Site Identity: 100 100 0 73.3 N.A. 26.6 13.3 N.A. 6.6 13.3 13.3 6.6 N.A. 13.3 6.6 13.3 13.3
P-Site Similarity: 100 100 13.3 73.3 N.A. 33.3 20 N.A. 20 26.6 20 33.3 N.A. 33.3 20 33.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 45 38.4 N.A.
Protein Similarity: N.A. N.A. N.A. 61.9 55.3 N.A.
P-Site Identity: N.A. N.A. N.A. 20 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 19 25 32 32 19 13 13 7 0 0 7 32 19 38 % A
% Cys: 0 7 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 0 7 0 0 0 0 7 0 25 13 7 7 7 % D
% Glu: 7 0 13 0 13 0 7 0 0 13 13 0 13 7 0 % E
% Phe: 7 0 0 0 0 7 7 0 0 0 0 0 7 0 0 % F
% Gly: 0 7 13 0 7 7 0 0 7 0 0 25 0 25 0 % G
% His: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 7 0 7 7 0 7 0 7 0 7 7 0 0 0 0 % I
% Lys: 0 0 7 0 7 7 19 0 0 7 0 7 0 7 7 % K
% Leu: 19 13 7 7 7 13 0 7 13 25 19 7 7 13 0 % L
% Met: 0 0 7 0 0 0 0 0 0 19 0 13 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 7 7 0 0 0 0 0 0 % N
% Pro: 13 50 0 0 13 19 7 13 0 13 0 0 0 13 13 % P
% Gln: 7 0 7 19 0 0 13 7 0 0 0 7 0 0 7 % Q
% Arg: 13 7 7 0 13 7 19 7 19 0 13 7 13 0 7 % R
% Ser: 0 0 0 7 7 13 7 38 25 13 13 0 19 7 13 % S
% Thr: 7 0 0 0 0 7 7 7 13 0 0 13 7 0 0 % T
% Val: 0 0 13 7 0 0 7 0 7 7 0 7 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _