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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GARS All Species: 32.12
Human Site: T603 Identified Species: 47.11
UniProt: P41250 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41250 NP_002038.2 739 83140 T603 R E G D E Q R T F F S F P A V
Chimpanzee Pan troglodytes XP_519025 739 83175 T603 R E G D E Q R T F F S F P A V
Rhesus Macaque Macaca mulatta XP_001086099 606 68263 H471 S C Y D L S C H A R A T K V P
Dog Lupus familis XP_532502 749 83638 T605 R E G D E Q R T F F S F P A V
Cat Felis silvestris
Mouse Mus musculus Q9CZD3 729 81859 T593 R E G D E Q R T F F S F P A V
Rat Rattus norvegicus Q5I0G4 637 72012 T501 R E G D E Q R T F F S F P A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521270 751 83825 R613 E P S F G L G R I L Y T V L E
Chicken Gallus gallus NP_001026681 685 77562 T549 R E G D E Q R T F F S F P A V
Frog Xenopus laevis NP_001089920 740 83613 T604 R Q G D E Q R T Y F T F P A I
Zebra Danio Brachydanio rerio XP_692410 764 86292 T628 R E G D E Q R T Y F S F P A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730022 765 85173 R629 L E H S F Q C R D G D E Q R C
Honey Bee Apis mellifera XP_391940 740 84354 E604 E H N F K A R E G D E K R T Y
Nematode Worm Caenorhab. elegans Q10039 742 84131 E607 E H S F R Q R E G D E Q R T F
Sea Urchin Strong. purpuratus XP_784166 684 77193 N549 H N F K V R E N D E Q R T Y F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23627 729 81925 T594 L Y E H C F S T R P S K A G D
Baker's Yeast Sacchar. cerevisiae P38088 667 75392 D531 S F W N R P E D N A R S V L S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 77.5 92.5 N.A. 91.6 82.2 N.A. 77.6 83.6 82.9 80.3 N.A. 55.8 58.6 53.9 56.9
Protein Similarity: 100 99.7 79.4 95.7 N.A. 95.6 85.2 N.A. 86.4 90.1 90.6 87.8 N.A. 70.8 74.7 70.8 72.8
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 0 100 73.3 86.6 N.A. 13.3 6.6 13.3 0
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 0 100 100 93.3 N.A. 13.3 13.3 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. 45 38.4 N.A.
Protein Similarity: N.A. N.A. N.A. 61.9 55.3 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 0 0 7 7 7 0 7 50 0 % A
% Cys: 0 7 0 0 7 0 13 0 0 0 0 0 0 0 7 % C
% Asp: 0 0 0 57 0 0 0 7 13 13 7 0 0 0 7 % D
% Glu: 19 50 7 0 50 0 13 13 0 7 13 7 0 0 7 % E
% Phe: 0 7 7 19 7 7 0 0 38 50 0 50 0 0 13 % F
% Gly: 0 0 50 0 7 0 7 0 13 7 0 0 0 7 0 % G
% His: 7 13 7 7 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 7 % I
% Lys: 0 0 0 7 7 0 0 0 0 0 0 13 7 0 0 % K
% Leu: 13 0 0 0 7 7 0 0 0 7 0 0 0 13 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 7 7 0 0 0 7 7 0 0 0 0 0 0 % N
% Pro: 0 7 0 0 0 7 0 0 0 7 0 0 50 0 7 % P
% Gln: 0 7 0 0 0 63 0 0 0 0 7 7 7 0 0 % Q
% Arg: 50 0 0 0 13 7 63 13 7 7 7 7 13 7 0 % R
% Ser: 13 0 13 7 0 7 7 0 0 0 50 7 0 0 7 % S
% Thr: 0 0 0 0 0 0 0 57 0 0 7 13 7 13 7 % T
% Val: 0 0 0 0 7 0 0 0 0 0 0 0 13 7 38 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 7 0 0 0 0 0 13 0 7 0 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _