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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GARS All Species: 19.39
Human Site: Y374 Identified Species: 28.44
UniProt: P41250 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41250 NP_002038.2 739 83140 Y374 N V A D L H L Y L Y S A K A Q
Chimpanzee Pan troglodytes XP_519025 739 83175 Y374 N V A D L H L Y L Y S A K A Q
Rhesus Macaque Macaca mulatta XP_001086099 606 68263 N247 S V L A Q L D N Y G Q Q E L T
Dog Lupus familis XP_532502 749 83638 Y376 N V A D L H L Y L Y S A K A Q
Cat Felis silvestris
Mouse Mus musculus Q9CZD3 729 81859 Y364 S V A D L C L Y L Y S A K A Q
Rat Rattus norvegicus Q5I0G4 637 72012 Y272 S V A D L Y L Y L Y S A K A Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521270 751 83825 D389 E H F V D P S D K Q H P K F P
Chicken Gallus gallus NP_001026681 685 77562 L320 S V A D L N I L L Y S S K A Q
Frog Xenopus laevis NP_001089920 740 83613 N375 N V A D L N L N L Y S S K A Q
Zebra Danio Brachydanio rerio XP_692410 764 86292 M399 N V A D L D I M L Y S S K A Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730022 765 85173 L405 G N I K S E K L T L Y S A C N
Honey Bee Apis mellifera XP_391940 740 84354 L380 T V K D L N V L L H S A C N Q
Nematode Worm Caenorhab. elegans Q10039 742 84131 L383 A K V A D Q K L V L F S A C N
Sea Urchin Strong. purpuratus XP_784166 684 77193 P325 T V A N L A I P L F P V D R Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23627 729 81925 F370 S D V A K L E F L M F P R E E
Baker's Yeast Sacchar. cerevisiae P38088 667 75392 S303 E I K D I K L S F L P R D V Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 77.5 92.5 N.A. 91.6 82.2 N.A. 77.6 83.6 82.9 80.3 N.A. 55.8 58.6 53.9 56.9
Protein Similarity: 100 99.7 79.4 95.7 N.A. 95.6 85.2 N.A. 86.4 90.1 90.6 87.8 N.A. 70.8 74.7 70.8 72.8
P-Site Identity: 100 100 6.6 100 N.A. 86.6 86.6 N.A. 6.6 66.6 80 73.3 N.A. 0 46.6 0 33.3
P-Site Similarity: 100 100 20 100 N.A. 93.3 100 N.A. 6.6 93.3 93.3 86.6 N.A. 6.6 66.6 13.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. 45 38.4 N.A.
Protein Similarity: N.A. N.A. N.A. 61.9 55.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 57 19 0 7 0 0 0 0 0 38 13 50 0 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 7 13 0 % C
% Asp: 0 7 0 63 13 7 7 7 0 0 0 0 13 0 0 % D
% Glu: 13 0 0 0 0 7 7 0 0 0 0 0 7 7 7 % E
% Phe: 0 0 7 0 0 0 0 7 7 7 13 0 0 7 0 % F
% Gly: 7 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % G
% His: 0 7 0 0 0 19 0 0 0 7 7 0 0 0 0 % H
% Ile: 0 7 7 0 7 0 19 0 0 0 0 0 0 0 0 % I
% Lys: 0 7 13 7 7 7 13 0 7 0 0 0 57 0 0 % K
% Leu: 0 0 7 0 63 13 44 25 69 19 0 0 0 7 0 % L
% Met: 0 0 0 0 0 0 0 7 0 7 0 0 0 0 0 % M
% Asn: 32 7 0 7 0 19 0 13 0 0 0 0 0 7 13 % N
% Pro: 0 0 0 0 0 7 0 7 0 0 13 13 0 0 7 % P
% Gln: 0 0 0 0 7 7 0 0 0 7 7 7 0 0 69 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 7 7 7 0 % R
% Ser: 32 0 0 0 7 0 7 7 0 0 57 32 0 0 0 % S
% Thr: 13 0 0 0 0 0 0 0 7 0 0 0 0 0 7 % T
% Val: 0 69 13 7 0 0 7 0 7 0 0 7 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 32 7 50 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _