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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GARS All Species: 31.52
Human Site: Y467 Identified Species: 46.22
UniProt: P41250 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41250 NP_002038.2 739 83140 Y467 G C A D R S C Y D L S C H A R
Chimpanzee Pan troglodytes XP_519025 739 83175 Y467 G C A D R S C Y D L S C H A R
Rhesus Macaque Macaca mulatta XP_001086099 606 68263 P335 S F R N E I S P R S G L I R V
Dog Lupus familis XP_532502 749 83638 Y469 G C A D R S C Y D L S C H A R
Cat Felis silvestris
Mouse Mus musculus Q9CZD3 729 81859 Y457 G C A D R S C Y D L S C H A R
Rat Rattus norvegicus Q5I0G4 637 72012 Y365 G C A D R S C Y D L S C H A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521270 751 83825 A477 Y A C D C W D A E A K T S Y G
Chicken Gallus gallus NP_001026681 685 77562 Y413 G C A D R S C Y D L S C H A R
Frog Xenopus laevis NP_001089920 740 83613 Y468 G C A D R S C Y D L S C H A R
Zebra Danio Brachydanio rerio XP_692410 764 86292 Y492 G C A D R S C Y D L L C H A R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730022 765 85173 C493 G W V E C V G C A D R S A Y D
Honey Bee Apis mellifera XP_391940 740 84354 A468 W I E C V G C A D R S A Y D L
Nematode Worm Caenorhab. elegans Q10039 742 84131 N471 G W I E C V G N A D R A C Y D
Sea Urchin Strong. purpuratus XP_784166 684 77193 A413 W V E C V G N A D R S C Y D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23627 729 81925 I458 G W I E C V G I A D R S A Y D
Baker's Yeast Sacchar. cerevisiae P38088 667 75392 S395 C V G C A D R S A Y D L T V H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 77.5 92.5 N.A. 91.6 82.2 N.A. 77.6 83.6 82.9 80.3 N.A. 55.8 58.6 53.9 56.9
Protein Similarity: 100 99.7 79.4 95.7 N.A. 95.6 85.2 N.A. 86.4 90.1 90.6 87.8 N.A. 70.8 74.7 70.8 72.8
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 6.6 100 100 93.3 N.A. 6.6 20 6.6 20
P-Site Similarity: 100 100 6.6 100 N.A. 100 100 N.A. 13.3 100 100 93.3 N.A. 13.3 26.6 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 45 38.4 N.A.
Protein Similarity: N.A. N.A. N.A. 61.9 55.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 50 0 7 0 0 19 25 7 0 13 13 50 0 % A
% Cys: 7 50 7 19 25 0 57 7 0 0 0 57 7 0 0 % C
% Asp: 0 0 0 57 0 7 7 0 63 19 7 0 0 13 19 % D
% Glu: 0 0 13 19 7 0 0 0 7 0 0 0 0 0 0 % E
% Phe: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 69 0 7 0 0 13 19 0 0 0 7 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 7 % H
% Ile: 0 7 13 0 0 7 0 7 0 0 0 0 7 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 50 7 13 0 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 0 7 7 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 7 0 50 0 7 0 7 13 19 0 0 7 50 % R
% Ser: 7 0 0 0 0 50 7 7 0 7 57 13 7 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % T
% Val: 0 13 7 0 13 19 0 0 0 0 0 0 0 7 7 % V
% Trp: 13 19 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 50 0 7 0 0 13 25 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _