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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IARS
All Species:
13.33
Human Site:
T818
Identified Species:
22.56
UniProt:
P41252
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41252
NP_002152.2
1262
144498
T818
E
E
L
I
D
K
K
T
E
S
A
V
S
Q
M
Chimpanzee
Pan troglodytes
XP_520691
1152
131723
Q745
K
E
I
V
V
I
H
Q
D
P
E
A
L
K
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541332
2763
310768
T2250
E
E
L
I
D
K
S
T
E
S
A
V
S
R
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU30
1262
144238
T818
E
E
L
I
D
K
K
T
E
N
A
V
S
R
M
Rat
Rattus norvegicus
NP_001094042
1262
144267
T818
E
E
L
I
D
K
K
T
E
N
A
V
S
R
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512705
1182
134676
L751
T
I
P
V
K
Y
P
L
K
E
V
V
V
I
H
Chicken
Gallus gallus
XP_414300
1264
144692
I818
E
D
L
I
D
R
K
I
E
S
A
V
S
C
L
Frog
Xenopus laevis
NP_001084397
1259
143978
I818
E
D
L
I
D
K
K
I
E
G
A
V
S
R
M
Zebra Danio
Brachydanio rerio
NP_956190
1271
145113
I818
E
S
L
I
D
Q
R
I
E
S
A
V
S
R
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730716
1229
141081
K826
M
M
P
V
S
Q
K
K
F
I
R
N
D
I
E
Honey Bee
Apis mellifera
XP_624023
1246
144330
I816
S
K
L
I
D
E
K
I
E
K
A
V
S
Y
M
Nematode Worm
Caenorhab. elegans
Q21926
1141
129993
R738
N
I
Y
I
R
L
N
R
K
R
V
K
G
D
N
Sea Urchin
Strong. purpuratus
XP_801899
1186
135049
M780
T
P
F
L
T
E
H
M
Y
Q
N
L
R
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P09436
1072
122965
I669
F
K
F
L
D
G
Q
I
A
L
L
K
K
M
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
N.A.
40.1
N.A.
90.5
90.7
N.A.
73.6
81.9
77.5
74.1
N.A.
52.8
57.4
52.1
60.3
Protein Similarity:
100
91.1
N.A.
42.8
N.A.
96.5
96.4
N.A.
82.9
91.4
87.6
87.1
N.A.
69.3
73.8
67
74.2
P-Site Identity:
100
6.6
N.A.
86.6
N.A.
86.6
86.6
N.A.
6.6
66.6
73.3
66.6
N.A.
6.6
60
6.6
0
P-Site Similarity:
100
40
N.A.
93.3
N.A.
100
100
N.A.
20
86.6
86.6
86.6
N.A.
20
73.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
47
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
62.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
58
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
15
0
0
65
0
0
0
8
0
0
0
8
8
8
% D
% Glu:
50
36
0
0
0
15
0
0
58
8
8
0
0
0
8
% E
% Phe:
8
0
15
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
8
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
15
0
0
0
0
0
0
8
8
% H
% Ile:
0
15
8
65
0
8
0
36
0
8
0
0
0
15
0
% I
% Lys:
8
15
0
0
8
36
50
8
15
8
0
15
8
8
0
% K
% Leu:
0
0
58
15
0
8
0
8
0
8
8
8
8
0
15
% L
% Met:
8
8
0
0
0
0
0
8
0
0
0
0
0
8
50
% M
% Asn:
8
0
0
0
0
0
8
0
0
15
8
8
0
0
8
% N
% Pro:
0
8
15
0
0
0
8
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
15
8
8
0
8
0
0
0
8
0
% Q
% Arg:
0
0
0
0
8
8
8
8
0
8
8
0
8
36
0
% R
% Ser:
8
8
0
0
8
0
8
0
0
29
0
0
58
0
8
% S
% Thr:
15
0
0
0
8
0
0
29
0
0
0
0
0
0
0
% T
% Val:
0
0
0
22
8
0
0
0
0
0
15
65
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
0
0
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _