KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IARS
All Species:
25.45
Human Site:
Y1021
Identified Species:
43.08
UniProt:
P41252
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41252
NP_002152.2
1262
144498
Y1021
K
A
K
S
E
G
T
Y
L
N
S
V
I
E
S
Chimpanzee
Pan troglodytes
XP_520691
1152
131723
H919
L
N
S
V
I
E
S
H
T
E
F
I
F
T
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541332
2763
310768
Y2453
K
A
K
S
E
G
K
Y
L
N
N
V
I
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU30
1262
144238
Y1021
N
A
K
S
E
G
R
Y
L
N
N
V
I
E
S
Rat
Rattus norvegicus
NP_001094042
1262
144267
Y1021
N
A
K
S
E
G
R
Y
L
S
N
V
I
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512705
1182
134676
Y925
K
A
Q
P
E
G
G
Y
L
D
S
V
I
K
S
Chicken
Gallus gallus
XP_414300
1264
144692
Y1021
R
S
H
P
E
G
D
Y
L
D
T
V
I
K
E
Frog
Xenopus laevis
NP_001084397
1259
143978
Y1021
Q
S
L
P
E
G
N
Y
L
Q
S
V
I
E
R
Zebra Danio
Brachydanio rerio
NP_956190
1271
145113
Y1021
R
C
Q
P
A
G
E
Y
L
H
Q
V
I
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730716
1229
141081
R1000
L
L
E
E
G
L
A
R
E
V
I
N
R
V
Q
Honey Bee
Apis mellifera
XP_624023
1246
144330
I1010
L
V
P
S
D
E
A
I
V
Y
Y
E
I
Q
D
Nematode Worm
Caenorhab. elegans
Q21926
1141
129993
Q912
V
A
D
Y
L
K
N
Q
I
T
E
S
E
L
E
Sea Urchin
Strong. purpuratus
XP_801899
1186
135049
G957
N
M
E
E
S
A
S
G
S
S
Q
Y
Q
A
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P09436
1072
122965
I843
N
I
R
E
K
K
T
I
S
L
K
T
P
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
N.A.
40.1
N.A.
90.5
90.7
N.A.
73.6
81.9
77.5
74.1
N.A.
52.8
57.4
52.1
60.3
Protein Similarity:
100
91.1
N.A.
42.8
N.A.
96.5
96.4
N.A.
82.9
91.4
87.6
87.1
N.A.
69.3
73.8
67
74.2
P-Site Identity:
100
0
N.A.
86.6
N.A.
80
73.3
N.A.
66.6
40
53.3
40
N.A.
0
13.3
6.6
0
P-Site Similarity:
100
26.6
N.A.
93.3
N.A.
86.6
86.6
N.A.
86.6
73.3
66.6
66.6
N.A.
6.6
33.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
47
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
62.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
43
0
0
8
8
15
0
0
0
0
0
0
8
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
8
0
0
15
0
0
0
0
8
% D
% Glu:
0
0
15
22
50
15
8
0
8
8
8
8
8
43
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% F
% Gly:
0
0
0
0
8
58
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
8
0
8
0
0
0
0
8
% H
% Ile:
0
8
0
0
8
0
0
15
8
0
8
8
65
0
0
% I
% Lys:
22
0
29
0
8
15
8
0
0
0
8
0
0
15
8
% K
% Leu:
22
8
8
0
8
8
0
0
58
8
0
0
0
15
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
29
8
0
0
0
0
15
0
0
22
22
8
0
0
0
% N
% Pro:
0
0
8
29
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
8
0
15
0
0
0
0
8
0
8
15
0
8
8
8
% Q
% Arg:
15
0
8
0
0
0
15
8
0
0
0
0
8
0
8
% R
% Ser:
0
15
8
36
8
0
15
0
15
15
22
8
0
0
36
% S
% Thr:
0
0
0
0
0
0
15
0
8
8
8
8
0
8
8
% T
% Val:
8
8
0
8
0
0
0
0
8
8
0
58
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
58
0
8
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _