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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IARS
All Species:
23.64
Human Site:
Y680
Identified Species:
40
UniProt:
P41252
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41252
NP_002152.2
1262
144498
Y680
E
E
E
I
E
F
L
Y
N
E
N
T
V
R
E
Chimpanzee
Pan troglodytes
XP_520691
1152
131723
K615
T
V
V
P
R
L
V
K
F
V
D
I
L
T
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541332
2763
310768
Y2112
E
E
E
M
E
F
I
Y
N
E
N
T
A
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU30
1262
144238
Y680
E
E
E
V
K
F
L
Y
N
E
H
T
V
R
E
Rat
Rattus norvegicus
NP_001094042
1262
144267
Y680
E
E
E
V
E
F
L
Y
N
E
H
T
V
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512705
1182
134676
R619
Q
T
E
M
A
A
Y
R
L
Y
T
V
V
P
R
Chicken
Gallus gallus
XP_414300
1264
144692
Y680
K
V
W
I
E
F
L
Y
N
E
N
T
V
K
E
Frog
Xenopus laevis
NP_001084397
1259
143978
F680
E
E
D
I
H
F
L
F
N
E
S
I
K
Q
Q
Zebra Danio
Brachydanio rerio
NP_956190
1271
145113
Y680
E
E
G
V
E
F
L
Y
N
E
R
T
S
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730716
1229
141081
E696
G
Q
Y
T
Y
D
R
E
R
H
L
K
N
M
D
Honey Bee
Apis mellifera
XP_624023
1246
144330
Y681
E
E
K
I
T
F
I
Y
D
D
F
K
N
V
C
Nematode Worm
Caenorhab. elegans
Q21926
1141
129993
N608
K
M
S
K
S
K
K
N
Y
P
D
P
M
L
I
Sea Urchin
Strong. purpuratus
XP_801899
1186
135049
K650
T
G
V
R
D
V
L
K
D
I
F
L
P
W
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P09436
1072
122965
S539
S
G
S
M
P
Y
A
S
Q
H
Y
P
F
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
N.A.
40.1
N.A.
90.5
90.7
N.A.
73.6
81.9
77.5
74.1
N.A.
52.8
57.4
52.1
60.3
Protein Similarity:
100
91.1
N.A.
42.8
N.A.
96.5
96.4
N.A.
82.9
91.4
87.6
87.1
N.A.
69.3
73.8
67
74.2
P-Site Identity:
100
0
N.A.
80
N.A.
80
86.6
N.A.
13.3
73.3
46.6
60
N.A.
0
33.3
0
6.6
P-Site Similarity:
100
20
N.A.
93.3
N.A.
100
100
N.A.
26.6
86.6
80
66.6
N.A.
13.3
60
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
47
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
62.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
8
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
8
0
8
8
0
0
15
8
15
0
0
0
8
% D
% Glu:
50
50
36
0
36
0
0
8
0
50
0
0
0
8
36
% E
% Phe:
0
0
0
0
0
58
0
8
8
0
15
0
8
0
8
% F
% Gly:
8
15
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
15
15
0
0
0
0
% H
% Ile:
0
0
0
29
0
0
15
0
0
8
0
15
0
0
8
% I
% Lys:
15
0
8
8
8
8
8
15
0
0
0
15
8
8
0
% K
% Leu:
0
0
0
0
0
8
50
0
8
0
8
8
8
8
0
% L
% Met:
0
8
0
22
0
0
0
0
0
0
0
0
8
8
0
% M
% Asn:
0
0
0
0
0
0
0
8
50
0
22
0
15
0
15
% N
% Pro:
0
0
0
8
8
0
0
0
0
8
0
15
8
8
0
% P
% Gln:
8
8
0
0
0
0
0
0
8
0
0
0
0
8
8
% Q
% Arg:
0
0
0
8
8
0
8
8
8
0
8
0
0
29
8
% R
% Ser:
8
0
15
0
8
0
0
8
0
0
8
0
8
8
0
% S
% Thr:
15
8
0
8
8
0
0
0
0
0
8
43
0
8
0
% T
% Val:
0
15
15
22
0
8
8
0
0
8
0
8
36
8
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
8
0
8
8
8
50
8
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _