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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IARS All Species: 36.06
Human Site: Y888 Identified Species: 61.03
UniProt: P41252 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41252 NP_002152.2 1262 144498 Y888 L S T D K N K Y G I R L R A E
Chimpanzee Pan troglodytes XP_520691 1152 131723 S810 M T S I K Q L S S E E L E Q F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_541332 2763 310768 Y2320 L S T D K N K Y G I R L R A E
Cat Felis silvestris
Mouse Mus musculus Q8BU30 1262 144238 Y888 L S T D K N K Y G I R L R A E
Rat Rattus norvegicus NP_001094042 1262 144267 Y888 L S T D K N K Y G I R L R A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512705 1182 134676 V816 L K G A F K T V M A S V K E L
Chicken Gallus gallus XP_414300 1264 144692 Y888 L S T N K D K Y G V R L R A E
Frog Xenopus laevis NP_001084397 1259 143978 Y888 V S T N K D K Y G I R L R A E
Zebra Danio Brachydanio rerio NP_956190 1271 145113 Y888 L S T D K D R Y G I R L R A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730716 1229 141081 R891 I L S E L N V R K L T L S S D
Honey Bee Apis mellifera XP_624023 1246 144330 Y886 V T T D K E K Y G V K L K A E
Nematode Worm Caenorhab. elegans Q21926 1141 129993 D803 F L M L P K P D E S L I D E T
Sea Urchin Strong. purpuratus XP_801899 1186 135049 Y845 R A T I P T K Y P L K E V V V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P09436 1072 122965 Y734 I D E L T N W Y I R F N R R R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.8 N.A. 40.1 N.A. 90.5 90.7 N.A. 73.6 81.9 77.5 74.1 N.A. 52.8 57.4 52.1 60.3
Protein Similarity: 100 91.1 N.A. 42.8 N.A. 96.5 96.4 N.A. 82.9 91.4 87.6 87.1 N.A. 69.3 73.8 67 74.2
P-Site Identity: 100 13.3 N.A. 100 N.A. 100 100 N.A. 6.6 80 80 86.6 N.A. 13.3 60 0 20
P-Site Similarity: 100 33.3 N.A. 100 N.A. 100 100 N.A. 20 100 100 100 N.A. 53.3 93.3 6.6 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 47 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 62.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 0 0 0 0 8 0 0 0 58 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 43 0 22 0 8 0 0 0 0 8 0 8 % D
% Glu: 0 0 8 8 0 8 0 0 8 8 8 8 8 15 58 % E
% Phe: 8 0 0 0 8 0 0 0 0 0 8 0 0 0 8 % F
% Gly: 0 0 8 0 0 0 0 0 58 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 15 0 0 15 0 0 0 0 8 43 0 8 0 0 0 % I
% Lys: 0 8 0 0 65 15 58 0 8 0 15 0 15 0 0 % K
% Leu: 50 15 0 15 8 0 8 0 0 15 8 72 0 0 8 % L
% Met: 8 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 15 0 43 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 15 0 8 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % Q
% Arg: 8 0 0 0 0 0 8 8 0 8 50 0 58 8 8 % R
% Ser: 0 50 15 0 0 0 0 8 8 8 8 0 8 8 0 % S
% Thr: 0 15 65 0 8 8 8 0 0 0 8 0 0 0 8 % T
% Val: 15 0 0 0 0 0 8 8 0 15 0 8 8 8 8 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 72 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _