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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K8
All Species:
30.91
Human Site:
Y445
Identified Species:
97.14
UniProt:
P41279
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41279
NP_005195.2
467
52925
Y445
L
K
R
Q
R
S
L
Y
I
D
L
G
A
L
A
Chimpanzee
Pan troglodytes
XP_001136851
572
63619
Y550
L
K
R
Q
R
S
L
Y
I
D
L
G
A
L
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544213
704
77443
Y682
L
K
R
Q
R
S
L
Y
I
D
L
G
A
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q07174
467
52923
Y445
L
R
R
Q
R
S
L
Y
I
D
L
G
A
L
A
Rat
Rattus norvegicus
Q63562
467
52789
Y445
L
R
R
Q
R
S
L
Y
I
D
L
G
A
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507627
553
62220
Y531
L
K
R
Q
R
S
L
Y
I
D
L
G
A
L
A
Chicken
Gallus gallus
XP_418581
468
53236
Y446
V
K
R
Q
R
S
L
Y
I
D
L
G
A
L
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692177
461
52316
Y439
S
K
K
K
G
S
L
Y
I
D
L
G
A
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.2
N.A.
64.4
N.A.
93.3
94
N.A.
76.6
83.7
N.A.
60.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
81.4
N.A.
65.3
N.A.
97.4
97.2
N.A.
80.4
92.9
N.A.
73.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
100
93.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
100
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% F
% Gly:
0
0
0
0
13
0
0
0
0
0
0
100
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% I
% Lys:
0
75
13
13
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
75
0
0
0
0
0
100
0
0
0
100
0
0
88
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
88
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
25
88
0
88
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
13
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _