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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCYAP1R1
All Species:
26.67
Human Site:
S346
Identified Species:
58.67
UniProt:
P41586
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41586
NP_001109.2
468
53314
S346
D
M
G
G
N
E
S
S
I
Y
L
R
L
A
R
Chimpanzee
Pan troglodytes
XP_001166482
471
53697
S349
D
M
G
G
N
E
S
S
I
Y
L
R
L
A
R
Rhesus Macaque
Macaca mulatta
XP_001108910
991
107712
S868
D
I
R
K
S
D
S
S
P
Y
S
R
L
A
R
Dog
Lupus familis
XP_539503
496
56923
T374
C
K
M
S
E
L
S
T
I
T
L
R
L
A
R
Cat
Felis silvestris
Mouse
Mus musculus
P70205
496
56621
T374
C
K
M
S
E
L
S
T
I
T
L
R
L
A
R
Rat
Rattus norvegicus
P32215
523
59619
T401
C
K
M
S
E
L
S
T
I
T
L
R
L
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518174
379
43974
L260
L
F
I
E
G
L
Y
L
F
T
L
L
V
E
T
Chicken
Gallus gallus
NP_001092076
471
53693
S349
D
I
G
G
N
E
S
S
I
Y
L
R
L
A
R
Frog
Xenopus laevis
NP_001079082
465
53406
S343
D
I
G
G
N
E
S
S
I
Y
L
R
L
A
R
Zebra Danio
Brachydanio rerio
Q68EK2
470
54084
S337
V
T
H
Q
A
K
S
S
L
Y
M
K
A
V
R
Tiger Blowfish
Takifugu rubipres
NP_001098685
444
51041
R324
S
I
Y
L
R
L
A
R
S
T
L
L
L
I
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
25.7
88
N.A.
87.5
82.7
N.A.
52.3
83
76
25.7
73.9
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
34.9
90.5
N.A.
91.1
86.2
N.A.
63.4
89.8
84.6
45.7
83.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
53.3
46.6
N.A.
46.6
46.6
N.A.
6.6
93.3
93.3
26.6
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
53.3
N.A.
53.3
53.3
N.A.
13.3
100
100
53.3
26.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
0
0
0
0
0
10
73
0
% A
% Cys:
28
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
46
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
28
37
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
37
37
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
37
10
0
0
0
0
0
64
0
0
0
0
10
0
% I
% Lys:
0
28
0
10
0
10
0
0
0
0
0
10
0
0
0
% K
% Leu:
10
0
0
10
0
46
0
10
10
0
82
19
82
0
0
% L
% Met:
0
19
28
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
37
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
10
0
0
10
0
0
0
73
0
0
82
% R
% Ser:
10
0
0
28
10
0
82
55
10
0
10
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
28
0
46
0
0
0
0
10
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
10
0
0
55
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _