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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCI
All Species:
11.82
Human Site:
S206
Identified Species:
18.57
UniProt:
P41743
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41743
NP_002731.4
596
68262
S206
P
V
M
P
M
D
Q
S
S
M
H
S
D
H
A
Chimpanzee
Pan troglodytes
XP_001148501
597
67369
L209
D
K
N
E
D
A
D
L
P
S
E
E
T
D
G
Rhesus Macaque
Macaca mulatta
XP_001089400
597
68263
S207
P
V
M
P
M
D
Q
S
S
M
H
S
D
H
A
Dog
Lupus familis
XP_535855
696
78257
S306
P
M
M
P
M
D
Q
S
P
M
P
S
D
H
V
Cat
Felis silvestris
Mouse
Mus musculus
Q62074
595
68185
Q205
E
P
M
M
P
M
D
Q
T
M
H
P
D
H
T
Rat
Rattus norvegicus
P09217
592
67715
D196
P
S
Q
E
P
P
V
D
D
K
N
D
G
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506164
360
41199
A9
S
T
R
E
S
G
K
A
S
S
S
L
G
L
Q
Chicken
Gallus gallus
XP_417561
606
69931
G210
P
S
Q
E
P
Q
L
G
D
K
N
D
E
V
D
Frog
Xenopus laevis
NP_001084068
588
67442
P198
S
V
I
P
M
D
P
P
G
M
H
S
D
H
S
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
P198
P
M
I
G
R
I
D
P
G
S
T
H
P
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
A245
L
G
A
D
G
D
G
A
P
G
Q
S
F
R
S
Honey Bee
Apis mellifera
XP_397273
590
68031
S193
Q
Q
M
P
S
T
E
S
Q
T
I
D
R
N
G
Nematode Worm
Caenorhab. elegans
Q19266
597
68017
G198
P
A
S
G
S
L
K
G
A
R
S
N
T
S
S
Sea Urchin
Strong. purpuratus
XP_780275
524
59689
G173
P
N
G
N
D
K
I
G
N
S
P
I
S
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P87253
1142
127954
T615
T
L
R
P
G
S
K
T
S
I
S
S
G
S
I
Conservation
Percent
Protein Identity:
100
66.6
96.8
84.3
N.A.
98.3
72.3
N.A.
59.9
71.4
89.7
88.7
N.A.
36.4
67.9
58.1
63.5
Protein Similarity:
100
78.5
97.4
84.9
N.A.
98.8
83.5
N.A.
60.4
83
94.4
92.9
N.A.
54
78.1
74.1
72.4
P-Site Identity:
100
0
100
73.3
N.A.
33.3
6.6
N.A.
6.6
6.6
60
6.6
N.A.
13.3
20
6.6
6.6
P-Site Similarity:
100
0
100
80
N.A.
40
13.3
N.A.
20
20
73.3
20
N.A.
26.6
33.3
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
23.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
7
0
14
7
0
0
0
0
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
14
34
20
7
14
0
0
20
34
7
20
% D
% Glu:
7
0
0
27
0
0
7
0
0
0
7
7
7
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
7
7
14
14
7
7
20
14
7
0
0
20
0
14
% G
% His:
0
0
0
0
0
0
0
0
0
0
27
7
0
34
7
% H
% Ile:
0
0
14
0
0
7
7
0
0
7
7
7
0
0
7
% I
% Lys:
0
7
0
0
0
7
20
0
0
14
0
0
0
0
0
% K
% Leu:
7
7
0
0
0
7
7
7
0
0
0
7
0
14
0
% L
% Met:
0
14
34
7
27
7
0
0
0
34
0
0
0
0
0
% M
% Asn:
0
7
7
7
0
0
0
0
7
0
14
7
0
7
0
% N
% Pro:
54
7
0
40
20
7
7
14
20
0
14
7
7
0
0
% P
% Gln:
7
7
14
0
0
7
20
7
7
0
7
0
0
0
7
% Q
% Arg:
0
0
14
0
7
0
0
0
0
7
0
0
7
7
0
% R
% Ser:
14
14
7
0
20
7
0
27
27
27
20
40
7
14
20
% S
% Thr:
7
7
0
0
0
7
0
7
7
7
7
0
14
0
7
% T
% Val:
0
20
0
0
0
0
7
0
0
0
0
0
0
14
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _