Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKCI All Species: 16.97
Human Site: S44 Identified Species: 26.67
UniProt: P41743 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41743 NP_002731.4 596 68262 S44 M I T H F E P S I S F E G L C
Chimpanzee Pan troglodytes XP_001148501 597 67369 C48 C E E V R D M C R L H Q Q H P
Rhesus Macaque Macaca mulatta XP_001089400 597 68263 S44 M I T H F E P S I S F E G L C
Dog Lupus familis XP_535855 696 78257 S144 M I T H F E P S I S F E G L C
Cat Felis silvestris
Mouse Mus musculus Q62074 595 68185 S44 M I T H F E P S I S F E G L C
Rat Rattus norvegicus P09217 592 67715 V44 F Q D L C E E V R D M C G L H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506164 360 41199
Chicken Gallus gallus XP_417561 606 69931 Y48 L I T N L D A Y I S Y D E L C
Frog Xenopus laevis NP_001084068 588 67442 C44 S I T F D G L C N E V R D M C
Zebra Danio Brachydanio rerio Q90XF2 588 67303 C44 S I S Y E G L C N E V R D M C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138 I92 C S H C R E F I W G I G K Q G
Honey Bee Apis mellifera XP_397273 590 68031 G44 E E M R T I C G F S A A G L D
Nematode Worm Caenorhab. elegans Q19266 597 68017 A44 F F A L L K D A C K Q H K K Q
Sea Urchin Strong. purpuratus XP_780275 524 59689 V24 L V K L F P T V P V R P G L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P87253 1142 127954 I254 S G T L S I R I L A V K D V D
Conservation
Percent
Protein Identity: 100 66.6 96.8 84.3 N.A. 98.3 72.3 N.A. 59.9 71.4 89.7 88.7 N.A. 36.4 67.9 58.1 63.5
Protein Similarity: 100 78.5 97.4 84.9 N.A. 98.8 83.5 N.A. 60.4 83 94.4 92.9 N.A. 54 78.1 74.1 72.4
P-Site Identity: 100 0 100 100 N.A. 100 20 N.A. 0 40 20 13.3 N.A. 6.6 20 0 20
P-Site Similarity: 100 13.3 100 100 N.A. 100 20 N.A. 0 73.3 26.6 33.3 N.A. 6.6 20 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 23.9
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 7 7 0 7 7 7 0 0 0 % A
% Cys: 14 0 0 7 7 0 7 20 7 0 0 7 0 0 47 % C
% Asp: 0 0 7 0 7 14 7 0 0 7 0 7 20 0 14 % D
% Glu: 7 14 7 0 7 40 7 0 0 14 0 27 7 0 0 % E
% Phe: 14 7 0 7 34 0 7 0 7 0 27 0 0 0 0 % F
% Gly: 0 7 0 0 0 14 0 7 0 7 0 7 47 0 7 % G
% His: 0 0 7 27 0 0 0 0 0 0 7 7 0 7 7 % H
% Ile: 0 47 0 0 0 14 0 14 34 0 7 0 0 0 0 % I
% Lys: 0 0 7 0 0 7 0 0 0 7 0 7 14 7 0 % K
% Leu: 14 0 0 27 14 0 14 0 7 7 0 0 0 54 0 % L
% Met: 27 0 7 0 0 0 7 0 0 0 7 0 0 14 0 % M
% Asn: 0 0 0 7 0 0 0 0 14 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 7 27 0 7 0 0 7 0 0 14 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 7 7 7 7 7 % Q
% Arg: 0 0 0 7 14 0 7 0 14 0 7 14 0 0 0 % R
% Ser: 20 7 7 0 7 0 0 27 0 40 0 0 0 0 0 % S
% Thr: 0 0 47 0 7 0 7 0 0 0 0 0 0 0 0 % T
% Val: 0 7 0 7 0 0 0 14 0 7 20 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 7 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _