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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCI
All Species:
45.15
Human Site:
T395
Identified Species:
70.95
UniProt:
P41743
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41743
NP_002731.4
596
68262
T395
S
E
G
H
I
K
L
T
D
Y
G
M
C
K
E
Chimpanzee
Pan troglodytes
XP_001148501
597
67369
T398
A
D
G
H
I
K
L
T
D
Y
G
M
C
K
E
Rhesus Macaque
Macaca mulatta
XP_001089400
597
68263
T396
S
E
G
H
I
K
L
T
D
Y
G
M
C
K
E
Dog
Lupus familis
XP_535855
696
78257
T495
S
E
G
H
I
K
L
T
D
Y
G
M
C
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q62074
595
68185
T394
S
E
G
H
I
K
L
T
D
Y
G
M
C
K
E
Rat
Rattus norvegicus
P09217
592
67715
T393
A
D
G
H
I
K
L
T
D
Y
G
M
C
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506164
360
41199
N182
S
T
F
C
G
T
P
N
Y
I
A
P
E
I
L
Chicken
Gallus gallus
XP_417561
606
69931
T407
A
E
G
H
I
K
L
T
D
Y
G
M
C
K
E
Frog
Xenopus laevis
NP_001084068
588
67442
T387
S
E
G
H
I
K
L
T
D
Y
G
M
C
K
E
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
T387
S
E
G
H
I
K
L
T
D
Y
G
M
C
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
A444
Q
E
G
H
C
K
L
A
D
F
G
M
C
K
E
Honey Bee
Apis mellifera
XP_397273
590
68031
T388
H
E
G
H
V
K
L
T
D
Y
G
M
C
K
E
Nematode Worm
Caenorhab. elegans
Q19266
597
68017
T394
A
E
G
H
I
K
L
T
D
Y
G
M
C
K
E
Sea Urchin
Strong. purpuratus
XP_780275
524
59689
N346
S
T
F
C
G
T
P
N
Y
I
A
P
E
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P87253
1142
127954
A959
L
D
G
H
I
K
I
A
D
Y
G
L
C
K
E
Conservation
Percent
Protein Identity:
100
66.6
96.8
84.3
N.A.
98.3
72.3
N.A.
59.9
71.4
89.7
88.7
N.A.
36.4
67.9
58.1
63.5
Protein Similarity:
100
78.5
97.4
84.9
N.A.
98.8
83.5
N.A.
60.4
83
94.4
92.9
N.A.
54
78.1
74.1
72.4
P-Site Identity:
100
86.6
100
100
N.A.
100
86.6
N.A.
6.6
93.3
100
100
N.A.
73.3
86.6
93.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
100
100
N.A.
80
93.3
100
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
23.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
27
0
0
0
0
0
0
14
0
0
14
0
0
0
0
% A
% Cys:
0
0
0
14
7
0
0
0
0
0
0
0
87
0
0
% C
% Asp:
0
20
0
0
0
0
0
0
87
0
0
0
0
0
0
% D
% Glu:
0
67
0
0
0
0
0
0
0
0
0
0
14
0
87
% E
% Phe:
0
0
14
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
87
0
14
0
0
0
0
0
87
0
0
0
0
% G
% His:
7
0
0
87
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
74
0
7
0
0
14
0
0
0
14
0
% I
% Lys:
0
0
0
0
0
87
0
0
0
0
0
0
0
87
0
% K
% Leu:
7
0
0
0
0
0
80
0
0
0
0
7
0
0
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
80
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
14
0
0
0
0
14
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
14
0
0
0
14
0
74
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
14
80
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _