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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKCI All Species: 8.79
Human Site: T9 Identified Species: 13.81
UniProt: P41743 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41743 NP_002731.4 596 68262 T9 P T Q R D S S T M S H T V A G
Chimpanzee Pan troglodytes XP_001148501 597 67369 G13 G P K M E G S G G R V R L K A
Rhesus Macaque Macaca mulatta XP_001089400 597 68263 T9 P T Q R D S S T M S H T V A G
Dog Lupus familis XP_535855 696 78257 A109 P T Q R D S S A M S H A I A G
Cat Felis silvestris
Mouse Mus musculus Q62074 595 68185 T9 P T Q R D S S T M S H T V A C
Rat Rattus norvegicus P09217 592 67715 M9 P S R T D P K M D R S G G R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506164 360 41199
Chicken Gallus gallus XP_417561 606 69931 K13 G S K V N L S K D I I R V K A
Frog Xenopus laevis NP_001084068 588 67442 M9 P T Q R D N T M S Q P S D H S
Zebra Danio Brachydanio rerio Q90XF2 588 67303 M9 P T L R D S T M S H P G E N P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138 R57 K E R A G F N R R R G A M R R
Honey Bee Apis mellifera XP_397273 590 68031 D9 P T Q T T E N D D I R V K I I
Nematode Worm Caenorhab. elegans Q19266 597 68017 E9 S S P T S L E E D G D I K L K
Sea Urchin Strong. purpuratus XP_780275 524 59689
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P87253 1142 127954 R219 L L K Q A L K R Y E E L H I D
Conservation
Percent
Protein Identity: 100 66.6 96.8 84.3 N.A. 98.3 72.3 N.A. 59.9 71.4 89.7 88.7 N.A. 36.4 67.9 58.1 63.5
Protein Similarity: 100 78.5 97.4 84.9 N.A. 98.8 83.5 N.A. 60.4 83 94.4 92.9 N.A. 54 78.1 74.1 72.4
P-Site Identity: 100 6.6 100 80 N.A. 93.3 13.3 N.A. 0 13.3 33.3 33.3 N.A. 0 20 0 0
P-Site Similarity: 100 26.6 100 86.6 N.A. 93.3 26.6 N.A. 0 33.3 53.3 40 N.A. 20 26.6 6.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 23.9
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 7 0 0 7 0 0 0 14 0 27 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % C
% Asp: 0 0 0 0 47 0 0 7 27 0 7 0 7 0 7 % D
% Glu: 0 7 0 0 7 7 7 7 0 7 7 0 7 0 0 % E
% Phe: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 14 0 0 0 7 7 0 7 7 7 7 14 7 0 20 % G
% His: 0 0 0 0 0 0 0 0 0 7 27 0 7 7 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 14 7 7 7 14 7 % I
% Lys: 7 0 20 0 0 0 14 7 0 0 0 0 14 14 7 % K
% Leu: 7 7 7 0 0 20 0 0 0 0 0 7 7 7 0 % L
% Met: 0 0 0 7 0 0 0 20 27 0 0 0 7 0 0 % M
% Asn: 0 0 0 0 7 7 14 0 0 0 0 0 0 7 0 % N
% Pro: 54 7 7 0 0 7 0 0 0 0 14 0 0 0 7 % P
% Gln: 0 0 40 7 0 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 0 0 14 40 0 0 0 14 7 20 7 14 0 14 7 % R
% Ser: 7 20 0 0 7 34 40 0 14 27 7 7 0 0 7 % S
% Thr: 0 47 0 20 7 0 14 20 0 0 0 20 0 0 0 % T
% Val: 0 0 0 7 0 0 0 0 0 0 7 7 27 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _